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Enabling technologies allied to green chemistry: synthesis of high value-added compounds from biomass derivatives

Grant number:20/11578-7
Support Opportunities:Program for Research on Bioenergy (BIOEN) - Regular Program Grants
Start date: February 01, 2021
End date: March 31, 2022
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Organic Chemistry
Principal Investigator:Júlio Cezar Pastre
Grantee:Júlio Cezar Pastre
Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
City of the host institution:Campinas
Associated researchers:Renan de Souza Galaverna

Abstract

Biofeedstocks in general and biowaste in particular represent an attractive source of useful chemical functionality, which to date is still largely untapped in terms of its application in the fine chemicals industry. Our group have identified continuous flow methods as a must use technology for the valorization of such materials. Indeed, many principles of Green Chemistry can be achieved with the adoption of new technologies that are inherently cleaner when compared to the current status quo. In this proposal, reactions under continuous flow regime as well as under microwave irradiation (MW) will be explored for the processing of an extremely rich and abundant matrix in Brazil: the biomass. The project comprises 3 strategic research axes, which the central objective is to explore the benefits of these two technologies for biomass processing for the obtention of: versatile platform chemicals - Axis 1, new chemicals and building blocks - Axis 2, and new functional materials - Axis 3. In the first axis, we will evaluate the synthesis of platform chemicals from carbohydrates, under MW irradiation. Design of experiments (DoE) will be employed in order to assess the reaction conditions and evaluate the effect of several parameters. In addition, we will pursue reaction conditions aligned with the principles of Green Chemistry, such as the use of green solvents, mild temperatures (lower energy expenditure) and reusable catalytic systems (ionic liquids from natural sources). In the second axis, renewable sources such as terpenes and chitin derivatives will be assessed. In this case, ethenolysis reactions of terpene derivatives will be evaluated aiming at the preparation of new compounds and synthetic intermediates. We will also investigate the use of N-acetyl-D-glucosamine in the synthesis of aminofuran compounds in batch (MW) and flow regime. Finally, in the third axis, we will evaluate the synthesis of new functional materials, also derived from biomass, such as the preparation of a heterogeneous palladium catalyst using a new solid support and novel polyurethanes as well as green polyesters. (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
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Scientific publications (8)
(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)
GOMES, GUSTAVO R.; MATTIOLI, RENAN R.; PASTRE, JULIO CEZAR. Amino Acid-Based Deep Eutectic Solvents in Biomass Processing- Recent Advances. Journal of the Brazilian Chemical Society, v. 33, n. 8, p. 9-pg., . (14/26378-2, 19/26450-9, 18/09861-2, 14/25770-6, 20/11578-7)
LABES, RICARDO; PASTRE, JULIO C.; INGHAM, RICHARD J.; BATTILOCCHIO, CLAUDIO; MARCON, HENRIQUE M.; DAMIAO, MARIANA C. F. C. B.; TRAN, DUC N.; LEY, STEVEN V.. Automated multistep synthesis of 2-pyrazolines in continuous flow. REACTION CHEMISTRY & ENGINEERING, v. 9, n. 3, p. 8-pg., . (14/25770-6, 15/18572-6, 14/26378-2, 20/11578-7, 18/25233-1)
GUSTAVO R. GOMES; RENAN R. MATTIOLI; JULIO CEZAR PASTRE. Amino Acid-Based Deep Eutectic Solvents in Biomass Processing - Recent Advances. Journal of the Brazilian Chemical Society, v. 33, n. 8, p. 815-823, . (18/09861-2, 19/26450-9, 14/25770-6, 14/26378-2, 20/11578-7)
GOMES, GUSTAVO R.; SCOPEL, EUPIDIO; ROCHA, NICOLA L.; BREITKREITZ, MARCIA C.; CORMANICH, RODRIGO A.; REZENDE, CAMILA A.; PASTRE, JULIO C.. Direct Ethyl Levulinate Production from Raw Lignocellulosic Biomass Mediated by a Novel Taurine-Based Imidazolium Ionic Liquid. ACS SUSTAINABLE CHEMISTRY & ENGINEERING, v. N/A, p. 13-pg., . (18/23769-1, 18/09861-2, 14/26378-2, 18/03910-1, 21/06661-5, 19/19360-3, 14/25770-6, 20/11578-7)
GALAVERNA, RENAN S.; FERNANDES, LUCAS P.; DA SILVA, VITOR H. MENEZES; DE SIERVO, ABNER; PASTRE, JULIO C.. Humins-Like Solid Support for Palladium Immobilization: Highly Efficient and Recyclable Catalyst for Cross-Coupling Reactions. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, v. 2022, n. 24, p. 11-pg., . (14/26378-2, 14/25770-6, 20/11578-7)
MARCON, HENRIQUE MAGRI; PASTRE, JULIO CEZAR. Continuous flow Meerwein-Ponndorf-Verley reduction of HMF and furfural using basic zirconium carbonate. RSC ADVANCES, v. 12, n. 13, p. 10-pg., . (14/26378-2, 18/25233-1, 14/25770-6, 20/11578-7)
GOMES, GUSTAVO R.; SCOPEL, EUPIDIO; BREITKREITZ, MARCIA C.; REZENDE, CAMILA A.; PASTRE, JULIO C.. Valorization of sugarcane bagasse C5-fraction by furfural production mediated by renewable glycine-based ionic liquid. INDUSTRIAL CROPS AND PRODUCTS, v. 191, p. 11-pg., . (18/09861-2, 18/23769-1, 14/26378-2, 21/06661-5, 20/11578-7, 19/19360-3, 14/25770-6)
GOMES, GUSTAVO RODRIGUES; BREITKREITZ, MARCIA CRISTINA; PASTRE, JULIO CEZAR. Ash Influence on the Ethyl Levulinate Production from Sugarcane Molasses Mediated by Taurine Hydrogen Sulfate. ACS SUSTAINABLE CHEMISTRY & ENGINEERING, v. 9, n. 40, p. 13438-13449, . (14/25770-6, 20/11578-7, 18/09861-2, 14/26378-2)