Non-invasive morphological evaluation and systemic inflammatory markers behavior in experimental model at tracheal stenosis

• Grant number: 21/03555-0
• Support Opportunities: Regular Research Grants
• Start date: May 01, 2022
• End date: December 31, 2024
• Field of knowledge: Health Sciences - Medicine - Surgery
• Principal Investigator: Paulo Francisco Guerreiro Cardoso
• Grantee: Paulo Francisco Guerreiro Cardoso
• Host Institution: Instituto do Coração Professor Euryclides de Jesus Zerbini (INCOR). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil
• Associated researchers: Helio Minamoto ; Henrique Takachi Moriya ; José Pinhata Otoch ; Marilia Cerqueira Leite Seelaender ; Paulo Manuel Pêgo-Fernandes

Abstract

Post-intubation tracheal stenosis is an inflammatory disease of the central airway with high prevalence. Its late diagnosis results from the clinical signs such as dyspnea that can only be detectable after a e70% reduction in the diameter of the tracheal lumen by the stenosis. The present study focuses on non-invasive methods for early detection of the stenosis in an experimental model of induced tracheal stenosis. (AU)