Morphological and molecular characterization of species Biomphalaria Preston, 1910...
Integrated risk mapping and targeted snail control to support schistosomiasis elim...
Grant number: | 07/03458-7 |
Support Opportunities: | Regular Research Grants |
Start date: | December 01, 2007 |
End date: | May 31, 2010 |
Field of knowledge: | Biological Sciences - Genetics - Animal Genetics |
Principal Investigator: | Roseli Tuan |
Grantee: | Roseli Tuan |
Host Institution: | Superintendência de Controle de Endemias (SUCEN). Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil |
Abstract
The ribosomal DNA internal transcribed spacer 2 (ITS2) and the partial mitochondrial 16S DNA has been shown to be a useful genetic markers for species identification and phylogenetic reconstruction in the genus of freshwater snails Biomphalaria (Preston 1910). Additionally, ITS2 studies in Biomphalaria uncovered significant intra-specific genetic variability suggesting the presence of cryptic species complexes. We will obtain ITS2 and 16S mitochondrial DNA sequences for B. tenagophila from the mainly basements at São Paulo State, Brazil and compare them B. tenagophila specimens from Rio Grande do Sul. We will address the following issues: polymorphism and divergence patterns, phylogenetic relationships, and the possible occurrence of species complex in Biomphalaria tenagophila. We will discuss the significance and implications for both epidemiological and evolutionary viewpoints, and highlights the need for future application of genetic markers for demarcating species boundaries. (AU)
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