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Fixation pattern in toxoplasmosis chorioretinitis

Grant number: 10/01714-9
Support type:Regular Research Grants
Duration: October 01, 2010 - September 30, 2012
Field of knowledge:Health Sciences - Medicine
Principal researcher:André Marcio Vieira Messias
Grantee:André Marcio Vieira Messias
Home Institution: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
Assoc. researchers:Rosália Maria Simões AntunesFoschini


Fixation pattern in patients suffering from central vision loss, such as, age related macular degeneration and Stargart disease, has been intensively investigated in the past 100 years. It is well known that its features, like the size of the scotoma and the styablility of the fixation are crucial for the success of visual rehabilitation strategy. Patients with macular chorioretinitis due to toxoplasmosis, i.e. from birth, are an excellent model for investigations on the physiology of eccentric fixation, because of the well-delimitated macular lesion, absence of other causes of visual deficit (i.e. aging), and the fact of the eccentric fixation is developed at young ages. The aim of this study is to determine spatial characteristics of the eccentric fixation, such as fixation locus, distance to the retinal lesion and stability, size of scotomas, and investigate the relationship between these parameters and reading, and visual acuity in patients showing unilateral or bilateral disease. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
ROBERTO SAAD FILHO; RENATA MORETO; RICARDO OKADA NAKAGHI; WILLIAM HADDAD; ROBERTO PINTO COELHO; ANDRÉ MESSIAS. Costs and outcomes of phacoemulsification for cataracts performed by residents. Arquivos Brasileiros de Oftalmologia, v. 83, n. 3, p. 209-214, Jun. 2020. Web of Science Citations: 0.
ANTUNES-FOSCHINI, ROSALIA M. S.; HO, WANLI; MESSIAS, ANDRE. Eccentric fixation patterns, clinical findings, and reading speed in patients with bilateral toxoplasmic macular retinochoroiditis. Arquivos Brasileiros de Oftalmologia, v. 81, n. 5, p. 401-407, SEP-OCT 2018. Web of Science Citations: 0.
MESSIAS, KATHARINA; JAEGLE, HERBERT; SARAN, RAFAEL; PINTO RUPPERT, ANDRE DOMINGOS; SIQUEIRA, RUBENS; JORGE, RODRIGO; MESSIAS, ANDRE. Psychophysically determined full-field stimulus thresholds (FST) in retinitis pigmentosa: relationships with electroretinography and visual field outcomes. DOCUMENTA OPHTHALMOLOGICA, v. 127, n. 2, p. 123-129, OCT 2013. Web of Science Citations: 9.

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