Analysis of chromosomal aberrations in childhood cancer through conventional and molecular cytogenetics

• Grant number: 10/15717-0
• Support Opportunities: Regular Research Grants
• Start date: December 01, 2010
• End date: November 30, 2012
• Field of knowledge: Biological Sciences - Genetics - Human and Medical Genetics
• Principal Investigator: Elvis Terci Valera
• Grantee: Elvis Terci Valera
• Host Institution: Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da USP (HCMRP). Ribeirão Preto , SP, Brazil
• City of the host institution: Ribeirão Preto
• Associated researchers: Carlos Alberto Scrideli ; Luiz Gonzaga Tone ; María Sol Brassesco Annichini

Abstract

Diferentes tipos de neoplasias humanas, tanto tumores sólidos como linfomas e leucemias, têm a sua progressão maligna acompanhada por múltiplas alterações cromossômicas numéricas e estruturais. Tem sido demonstrado que diferentes regiões cromossômicas são susceptíveis à instabilidade genômica e geralmente estas se acham associados a genes que contribuem para o processo tumoral. Além disso, a correta identificação de tais aberrações auxilia no diagnóstico, prognóstico, classificação das neoplasias e na decisão de terapia a ser utilizada. (AU)

Scientific publications

(6)

(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)

BRASSESCO, MARIA SOL; VALERA, ELVIS TERCI; MEYER, CLAUS; MARSCHALEK, ROLF; LOPES, BRUNO ALMEIDA; DE PAULA QUEIROZ, ROSANE GOMES; CALADO, RODRIGO DE TOCANTINS; SCRIDELI, CARLOS ALBERTO; TONE, LUIZ GONZAGA. A new complex rearrangement in infant ALL:t(X;11;17)(p11.2;q23;q12). CANCER GENETICS, v. 228, p. 110-114, DEC 2018. (10/15717-0, 15/20142-0)

FERRAZ, SABRINE TEIXEIRA; VALERA, ELVIS TERCI; BRASSESCO, MARIA SOL; DE OLIVEIRA, RICARDO SANTOS; DOS SANTOS, ANTONIO CARLOS; SAGGIORO, FABIANO PINTO; NEDER, LUCIANO; SCRIDELI, CARLOS ALBERTO; TONE, LUIZ GONZAGA. Intracranial teratoma in children: The role of chromosome 21 trisomy. NEUROPATHOLOGY, v. 34, n. 2, p. 197-200, APR 2014. (10/15717-0)

VALERA, ELVIS TERCI; FERRAZ, SABRINE TEIXEIRA; BRASSESCO, MARIA SOL; ZHEN, XIUMEI; SHEN, YIPING; SANTOS, ANTONIO CARLOS DOS; NEDER, LUCIANO; OLIVEIRA, RICARDO SANTOS; SCRIDELI, CARLOS ALBERTO; TONE, LUIZ GONZAGA. Mowat-Wilson syndrome: the first report of an association with central nervous system tumors. CHILD'S NERVOUS SYSTEM, v. 29, n. 12, p. 2151-2155, DEC 2013. (10/15717-0)

BRASSESCO, MARIA SOL; DARRIGO, JR., LUIZ GUILHERME; VALERA, ELVIS TERCI; OLIVEIRA, RICARDO SANTOS; YAMAMOTO, YULIE APARECIDA; DE CASTRO BARROS, MARCUS VINICIUS; TONE, LUIZ GONZAGA. Giant-cell glioblastoma of childhood associated with HIV-1 and JC virus coinfection. CHILD'S NERVOUS SYSTEM, v. 29, n. 8, p. 1387-1390, AUG 2013. (10/15717-0)

ENGEL, EDGARD EDUARD; BRASSESCO, MARIA SOL; VALERA, ELVIS TERCI; NOGUEIRA-BARBOSA, MARCELLO HENRIQUE; DE ALMEIDA SANTOS YAMASHITA, MAURICIO EIJI; SCRIDELI, CARLOS ALBERTO; TONE, LUIZ GONZAGA. Clinico-genetic aspects of a pediatric non-neurofibromatosis type 1 malignant triton tumor with loss of chromosome X. PEDIATRIC BLOOD & CANCER, v. 59, n. 7, p. 1320-1323, DEC 2012. (10/15717-0, 10/16652-9)

VALERA, ELVIS TERCI; BRASSESCO, MARIA SOL; SCRIDELI, CARLOS ALBERTO; DE CASTRO BARROS, MARCUS VINICIUS; SANTOS, ANTONIO CARLOS; OLIVEIRA, RICARDO SANTOS; MACHADO, HELIO RUBENS; TONE, LUIZ GONZAGA. Are patients with encephalocraniocutaneous lipomatosis at increased risk of developing low-grade gliomas?. CHILD'S NERVOUS SYSTEM, v. 28, n. 1, p. 19-22, JAN 2012. (10/15717-0, 10/16652-9)