FAPESP/LICR Human cancer genome project - sequencing center QV3

• Grant number: 99/03661-9
• Support Opportunities: Genome Research Grants
• Start date: June 01, 1999
• End date: June 30, 2001
• Field of knowledge: Biological Sciences - Physiology
• Agreement: Ludwig Institute
• Principal Investigator: Edna Teruko Kimura
• Grantee: Edna Teruko Kimura
• Host Institution: Instituto de Ciências Biomédicas (ICB). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

The FAPESP/LICR Human Cancer Genome Program aims to identify the genes expressed in human tumors. The compilation of gene coding region (open reading frame) is based in ORESTES method that is able to preferentially detect central coding portions of the expressed gene. The preliminary project goal is generating around 600.000 ESTs sequences expressed in the human genes, to be compared with existing data in Gene Data Banks (GenBank, Unigene, etc) by computational analysis; and then to make the data accessible through deposition in GeneBank. Our laboratory is a Sequencing Center (QV3) integrated to the QV Center: (Coordinator - Sergio Verjovski-Almeida). We are responsible for preparing one-fifth (26.000) of the templates to be sequenced in the QV Center of an estimated total of 130.000. (AU)