Acquisition of a flow cytometer for the specific separation of cells

• Grant number: 09/54012-4
• Support Opportunities: Multi-user Equipment Program
• Start date: August 01, 2010
• End date: July 31, 2012
• Field of knowledge: Biological Sciences - Pharmacology - General Pharmacology
• Principal Investigator: Sérgio Henrique Ferreira
• Grantee: Sérgio Henrique Ferreira
• Host Institution: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• City of the host institution: Ribeirão Preto
• EMU web page: Página do Equipamento Multiusuário não informada
• Type of equipment: Tipo de Equipamento Multiusuário não informado
• Manufacturer: Fabricante não informado
• Model: Modelo não informado

Abstract

The acquisition of a flow cytometer will be of key importance to quantitatively and qualitatively maximize the scientific production of the USP Ribeirão Preto School of Medicine and of other schools on the campus. This equipment will allow the purification of different cell types, which are used in investigations of cell-cell interaction, host-parasite interaction and intracellular mechanisms involved in controlling microbial infections. It will also allow the identification of cells that are sources or targets of inflammatory mediators in different models of inflammatory diseases, sepsis and inflammatory pain, as well as to determine the mechanisms of action of anti-inflammatory, analgesic and antimicrobial drugs. These studies could culminate in the identification of the pathophysiological mechanisms involved in these diseases and contribute to the development of new drugs. Approval of this FAPESP Multi-user Equipment Program request will also contribute to the development of theses and dissertations by students in various postgraduate programs, including pharmacology, immunology, biochemistry, molecular biology, cellular biology and clinical medicine. (AU)