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Acquisition of a flow cytometer for the specific separation of cells

Grant number: 09/54012-4
Support type:Multi-user Equipment Program
Duration: August 01, 2010 - July 31, 2012
Field of knowledge:Biological Sciences - Pharmacology
Principal Investigator:Sérgio Henrique Ferreira
Grantee:Sérgio Henrique Ferreira
Home Institution: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
EMU web page: Página do Equipamento Multiusuário não informada
Use scheduling: E-mail de agendamento não informado

Abstract

The acquisition of a flow cytometer will be of key importance to quantitatively and qualitatively maximize the scientific production of the USP Ribeirão Preto School of Medicine and of other schools on the campus. This equipment will allow the purification of different cell types, which are used in investigations of cell-cell interaction, host-parasite interaction and intracellular mechanisms involved in controlling microbial infections. It will also allow the identification of cells that are sources or targets of inflammatory mediators in different models of inflammatory diseases, sepsis and inflammatory pain, as well as to determine the mechanisms of action of anti-inflammatory, analgesic and antimicrobial drugs. These studies could culminate in the identification of the pathophysiological mechanisms involved in these diseases and contribute to the development of new drugs. Approval of this FAPESP Multi-user Equipment Program request will also contribute to the development of theses and dissertations by students in various postgraduate programs, including pharmacology, immunology, biochemistry, molecular biology, cellular biology and clinical medicine. (AU)