Importance of local damage induced by snake venom metalloproteinases in the induction of thrombocytopenia in envenomations

• Grant number: 10/52559-3
• Support Opportunities: Regular Research Grants
• Start date: August 01, 2011
• End date: July 31, 2013
• Field of knowledge: Biological Sciences - Pharmacology - Toxicology
• Agreement: CONICET
• Principal Investigator: Marcelo Larami Santoro
• Grantee: Marcelo Larami Santoro
• Principal researcher abroad: María Elisa Peichoto
• Institution abroad: Universidad Nacional del Nordeste (UNNE), Argentina
• Host Institution: Instituto Butantan. Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil
• Associated research grant: 10/08162-1 - Contribution of local injury evoked by Bothrops jararaca snake venom to the genesis of systemic hemostatic disturbances, AP.R

Scientific publications

(4)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ELISA PEICHOTO, MARIA; SANTORO, MARCELO LARAMI. Patagonfibrase modifies protein expression of tissue factor and protein disulfide isomerase in rat skin. Toxicon, v. 119, p. 330-335, SEP 1 2016. (10/08162-1, 10/52559-3, 13/25177-0)

SANCHEZ, M. N.; TIMONIUK, A.; MARUNAK, S.; TEIBLER, P.; ACOSTA, O.; PEICHOTO, M. E.. Biochemical and biological analysis of Philodryas baroni (Baron's Green Racer; Dipsadidae) venom: Relevance to the findings of human risk assessment. HUMAN & EXPERIMENTAL TOXICOLOGY, v. 33, n. 1, p. 22-31, JAN 2014. (10/52559-3)

ELISA PEICHOTO, MARIA; ZYCHAR, BIANCA CESTARI; LUIZ TAVARES, FLAVIO; GONCALVES, LUIS ROBERTO CAMARGO; ACOSTA, OFELIA; SANTORO, MARCELO LARAMI. Inflammatory effects of patagonfibrase, a metalloproteinase from Philodryas patagoniensis (Patagonia Green Racer; Dipsadidae) venom. Experimental Biology and Medicine, v. 236, n. 10, p. 1166-1172, OCT 2011. (08/02996-8, 10/52559-3, 10/08162-1)

YAMASHITA, KARINE M.; ALVES, ANDRE F.; BARBARO, KATIA C.; SANTORO, MARCELO L.. Bothrops jararaca Venom Metalloproteinases Are Essential for Coagulopathy and Increase Plasma Tissue Factor Levels during Envenomation. PLoS Neglected Tropical Diseases, v. 8, n. 5, MAY 2014. (10/08162-1, 10/02568-6, 10/52559-3)