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Noninvasive assessment of the stroke volume using electrical impedance tomography and its implications of the functional hemodynamic monitoring

Grant number: 11/50312-3
Support type:Regular Research Grants
Duration: July 01, 2011 - June 30, 2013
Field of knowledge:Health Sciences - Medicine
Principal Investigator:Eduardo Leite Vieira Costa
Grantee:Eduardo Leite Vieira Costa
Home Institution: Hospital Sírio-Libanês. Sociedade Beneficente de Senhoras (SBSHSL). São Paulo , SP, Brazil

Abstract

Invasive hemodynamic monitoring with pulmonary artery catheters is associated with a higher incidence of complications and even increased mortality. Conversely, hemodynamic optimization guided by clinical variables alone was shown to be inferior to that guided by more invavise parameters. In this context, the minimally invasive hemodynamic monitoring emerged, as well as the functional hemodynamic monitoring, which takes advantage of the cardiopulmonary interactions to guide volume replacement of critically ill patients. These techniques can be used in a limited clinical scope, however, i.e. in sedated patients on mechanical ventilation with high tidal volumes, without inspiratory efforts, and without arrhythmias. The Electrical Impedance Tomography (EIT) is a portable, noninvasive, and radiation-free monitoring tool, which allows assessment of ventilation and perfusion at the bedside. In the present study, we aim to develop a tool based on EIT to assess the hemodynamics, specifically the determination of right ventricular stroke volume and its variation with the respiratory cycle. Our hypothesis is that this information will increase the accuracy of the functional hemodynamic variables, especially in cases where their use is limited. (AU)