| Grant number: | 06/02523-7 |
| Support Opportunities: | Research Grants - Young Investigators Grants |
| Start date: | March 01, 2007 |
| End date: | February 28, 2009 |
| Field of knowledge: | Physical Sciences and Mathematics - Chemistry - Physical-Chemistry |
| Principal Investigator: | Monica Andrea Pickholz |
| Grantee: | Monica Andrea Pickholz |
| Host Institution: | Instituto de Biologia (IB). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil |
Abstract
This proposal aims at the implementation of a new research line in the field of computer simulations, inside the Jovem Pesquisador Program of FAPESP. It will be developed with the biomembranes group, headed by Prof. Eneida de Paula, at the Biochemistry Department of the Institute of Biology of UNICAMP. In this project, we propose to use computer simulations techniques to investigate, at the microscopic level, the interaction of local anesthetics with biological membranes. The study will focus the structural and dynamical properties (at the nanosecond time scale) of lipid bilayers and liposome at the biologically relevant phases. The project explores inter/multidisciplinary approach for the investigation of biological phenomena, where we combine competences from physics, biochemistry, and computer simulations. With this approach we expect to develop a scientifically rich environment for the researchers and students. (AU)
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