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Study of oxidative profile and biochemical variables of horses fed with different lipid sources

Grant number: 11/18130-2
Support type:Regular Research Grants
Duration: December 01, 2011 - November 30, 2013
Field of knowledge:Agronomical Sciences - Veterinary Medicine
Principal Investigator:Maria Claudia Araripe Sucupira
Grantee:Maria Claudia Araripe Sucupira
Home Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Assoc. researchers:Wilson Roberto Fernandes

Abstract

The search for the best performance and health of horses has stimulated studies on nutrition of this species. The large energy requirement of these animals can be achieved by diets rich in fatty acids instead of carbohydrates whose excess increases the risk of digestive and metabolic disorders. Oils of different plants and animals origin have the common characteristic of providing large amounts of energy, but differ in properties related to the active components. Depending on the origin those oils content, for example, omega-3, omega-6 and gama-oryzanol. These active substances can influence the oxidative metabolism, inflammation and immune response may assign benefits to its use in the diet of horses in metabolic imbalance. This study aims to compare the effect of oral supplementation with different sources of lipid antioxidant and immunological parameters as well as the relationship of these parameters with biochemical variables and liver lipid metabolism in horses. It will be use 5 horses in the statistical model "Latin Square". The animals will be fed five diets supplemented with the energy content of different lipid sources, they are: rice bran oil business, commercial fish oil, salmon oil, soybean oil (positive control) and mineral oil (negative control). The variables that will be analyzed are biochemical and oxidative metabolism markers and aspects of cell-mediated immunity. (AU)