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Effect of female hormones on pain sensitivity, bite force and masticatory performance of TMD patients

Abstract

Temporomandibular disorders (TMD) is a common painful condition, especially in women during the reproductive phase. The purpose of this study is to evaluate whether hormonal fluctuations occurring during the menstrual cycle alter pain sensitivity, maximum bite force and masticatory performance of volunteers with TMD. Fifty volunteers will be selected and divided into two groups of twenty five: (group 1) subjects presenting TMD and using oral contraceptives (control), and (group 2) subjects presenting TMD and not using oral contraceptives (experimental). The diagnosis of TMD will be accomplished through the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD). The presence of pain will be measured by visual analogue scale where the volunteer will point the pain intensity before evaluation of masticatory function. Bilateral bite force will be evaluated by means of sensors placed in the region of molar teeth, coupled with the amplifier equipment. The masticatory performance will be evaluated by the sieve method using an artificial food. All variables will be measured in the four phases of one complete menstrual cycle, identified by ovulation test. Next, all subjects will receive stabilizing occlusal appliances, and after 2 months the variables will be evaluated once again in four phases of the menstrual cycle for a month. The results will be first submitted to exploratory data analysis and then will be applied the appropriate statistical test. (AU)

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
REIS VILANOVA, LARISSA SOARES; SIMEK VEGA GONCALVES, THAIS MARQUES; MEIRELLES, LIS; RODRIGUES GARCIA, RENATA CUNHA MATHEUS. Hormonal Fluctuations Intensify Temporomandibular Disorder Pain Without Impairing Masticatory Function. International Journal of Prosthodontics, v. 28, n. 1, p. 72-74, JAN-FEB 2015. Web of Science Citations: 9.
REIS VILANOVA, LARISSA SOARES; SIMEK VEGA GONCALVES, THAIS MARQUES; PIMENTEL, MARCELE JARDIM; BAVIA, PAULA FURLAN; MATHEUS RODRIGUES GARCIA, RENATA CUNHA. MASTICATION MOVEMENTS AND SLEEP QUALITY OF PATIENTS WITH MYOFASCIAL PAIN: OCCLUSAL DEVICE THERAPY IMPROVEMENTS. JOURNAL OF PROSTHETIC DENTISTRY, v. 112, n. 6, p. 1330-1336, DEC 2014. Web of Science Citations: 2.

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