2nd São Paulo Advanced School on Primary Immunodeficiencies | São Paulo – SP

• Grant number: 12/50308-9
• Support type: Research Grants - Organization of Scientific Meeting - São Paulo School of Advanced Science
• Duration: August 01, 2012 - March 31, 2013
• Field of knowledge: Health Sciences - Medicine - Medical Clinics
• Principal researcher: Magda Maria Sales Carneiro-Sampaio
• Grantee: Magda Maria Sales Carneiro-Sampaio
• Home Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

The 2nd São Paulo Advanced School on Primary Immunodeficiencies focuses on the subject of the autoimmunity and immunodeficiency interface. The goal is to understand the mechanisms for induction and maintenance of tolerance to the own antigens – a major theme in Immunology. A high-level group of international and Brazilian researchers gathers in the meeting. Beyond the lectures, the school contemplates many activities, such as student presentations, poster viewing session, discussion of practical aspects of patient management, and so on. This is the second ESPCA within the theme of primary immunodeficiencies (PIDs), the first held in November 2010 in the first call of this program. PIDs are a large and heterogeneous group of about 180 different monogenics defects, considered as true "knock-outs", whose study represents a unique opportunity, still little explored, to understand how the human immune system. While ESPCA-PID I focused on the study of the physiology of the immune system, in particular the mechanisms of resistance in the second we intend to address the interface between auto-immunities and immunodeficiency, seeking to understand the mechanisms of induction and maintenance of tolerance to antigens – a key issue within the Immunology. (AU)