"Dentin bonding agents: bond strength and antibacterial activity"

• Grant number: 11/17841-2
• Support Opportunities: Regular Research Grants
• Start date: October 01, 2012
• End date: September 30, 2014
• Field of knowledge: Health Sciences - Dentistry - Dental Clinics
• Principal Investigator: Marcelo Giannini
• Grantee: Marcelo Giannini
• Host Institution: Faculdade de Odontologia de Piracicaba (FOP). Universidade Estadual de Campinas (UNICAMP). Piracicaba , SP, Brazil
• Associated researchers: Brenda Paula Figueiredo de Almeida Gomes

Abstract

The evolution of the adhesive ystems have provided improvement of the quality of the marginal sealing and the durability of the restorations. Some of them contain monomers solvents, initiators and also, fluoride, filler particles and antibacterial agents, which were little investigated. The objective of this study is to evaluate the bond strength and the antibacterial activity of three adhesive systems. For the dentin bond strength test, human teeth will be used. The bond strength test will performed after 1 week after specimen preparation and after one year of artificial saliva storage. For the antibacterial activity analysis, four strict anaerobic bacteria (Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum and Peptostreptococcus micros) and facultatively anaerobic bacteria (Staphylococcus aureus, Actinomyces naeslundii, Lactobacillus casei and Streptococcus mutans). The antibacterial activity analysis will include the inhibition halos, minimal inhibitory concentration and bactericidal minimum concentration, which will determined for all bacterial samples. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ANDRE, CAROLINA BOSSO; FIGUEIREDO ALMEIDA GOMES, BRENDA PAULA; DUQUE, THAIS MAGESTE; STIPP, RAFAEL NOBREGA; CHAN, DANIEL CHI NGAI; BOVI AMBROSANO, GLAUCIA MARIA; GIANNINI, MARCELO. Dentine bond strength and antimicrobial activity evaluation of adhesive systems. Journal of Dentistry, v. 43, n. 4, p. 466-475, APR 2015. (11/17841-2, 10/13599-0)

ANDRE, CAROLINA BOSSO; FIGUEIREDO ALMEIDA GOMES, BRENDA PAULA; DUQUE, THAIS MAGESTE; ROSALEN, PEDRO LUIS; CHAN, DANIEL CHI NGAI; BOVI AMBROSANO, GLAUCIA MARIA; GIANNINI, MARCELO. Antimicrobial activity, effects on Streptococcus mutans biofilm and interfacial bonding of adhesive systems with and without antibacterial agent. INTERNATIONAL JOURNAL OF ADHESION AND ADHESIVES, v. 72, p. 123-129, JAN 2017. (11/17841-2, 10/13599-0)