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Monitoring of electrolyte and acid-base alterations in horses submitted to the 160 km endurance race


The effort of endurance race is characterized by induction, in the athletes of the equine species, dehydration associated with considerable changes in electrolyte status and changes in acid-base homeostasis. The objective of this project will monitor changes in electrolyte and acid-base balance of the purebred Arabian horses, competing in a FEI*** 160 km. Sixteen horses, males and females, adults who participate in an endurance race horses, three star FEI (CEI3 *) 160 km away, will be monitored and divided into two groups, finalists (F) and eliminated (E). Venous blood samples will be collected before the start and during the race. Samples will also be obtained in the recovery period, immediately, two fifteen hours after the effort. To study the possible changes in acid-base homeostasis variables will be quantified venous blood gas and electrolyte as pH, partial pressure of carbon dioxide (PCO2), partial pressure of oxygen (PO2), base excess (BEecf), bicarbonate (HCO3-), total carbon dioxide (TCO2), oxygen saturation (sO2%), sodium (Na+), potassium (K+), chloride (Cl-) ionized calcium (Ca++) and strong ion different (SID). Other variables such as hematocrit, hemoglobin, total protein, albumin, globulin, urea, inorganic phosphorus, blood lactate and glucose concentrations will also be determined. In order to compare the variables obtained in the competition within each assessment stage, will be held analysis of variance (ANOVA). For the statistical differences detected in the F test will be held the Tukey test. Also will be apply the t test for unpaired comparison of means (independent samples) groups of finalists and eliminated. (AU)

Scientific publications (4)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
RESTAN, ALEJANDRO Z.; ZACCHE, EVANDRO; DA SILVA, SAMARA B.; CERQUEIRA, JULIANA A.; CARFIOFI, AULUS C.; QUEIROZ-NETO, ANTONIO; CAMACHO, APARECIDO A.; FERRAZ, GUILHERME C. Lactate and glucose thresholds and heart rate deflection points for Beagles during intense exercise. AMERICAN JOURNAL OF VETERINARY RESEARCH, v. 80, n. 3, p. 284-293, MAR 2019. Web of Science Citations: 0.
CERQUEIRA, JULIANA APARECIDA; ZAMORA RESTAN, WILMER ALEJANDRO; FONSECA, MAYARA GONCALVES; CATANANTI, LUCAS AZEVEDO; MENDES DE ALMEIDA, MARIA LUIZA; FERINGER JUNIOR, WALTER HEINZ; PEREIRA, GENER TADEU; CARCIOFI, AULUS CAVALIERI; FERRAZ, GUILHERME DE CAMARGO. Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogs. Research in Veterinary Science, v. 121, p. 31-39, DEC 2018. Web of Science Citations: 2.
LAGE, J.; FONSECA, M. G.; DE BARROS, G. G. M.; FERINGER-JUNIOR, W. H.; PEREIRA, G. T.; FERRAZ, G. C. Workload of official contests, net cost of transport, and metabolic power of Mangalarga Marchador horses of marcha batida or picada gaits. JOURNAL OF ANIMAL SCIENCE, v. 95, n. 6, p. 2488-2495, JUN 2017. Web of Science Citations: 2.
BERKMAN, C.; PEREIRA, M. C.; NARDI, K. B.; PEREIRA, G. T.; SOARES, O. A. B.; RESTAN, W. A. Z.; QUEIROZ-NETO, A.; FERRAZ, G. C. Agreement between i-STAT and YSI 2300 devices to determine lactate concentrations in dogs undergoing exercise. COMPARATIVE EXERCISE PHYSIOLOGY, v. 12, n. 2, p. 75-82, 2016. Web of Science Citations: 2.

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