Biophysical function of viral fusion peptides from HIV and Dengue virus

• Grant number: 13/50319-3
• Support Opportunities: Regular Research Grants
• Start date: October 01, 2013
• End date: September 30, 2014
• Field of knowledge: Biological Sciences - Biochemistry
• Agreement: Ohio State University
• Principal Investigator: Eduardo Maffud Cilli
• Grantee: Eduardo Maffud Cilli
• Principal researcher abroad: Dennis Bong
• Institution abroad: Ohio State University, Columbus, United States
• Host Institution: Instituto de Química (IQ). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brazil
• Associated research grant: 12/15346-7 - Antimicrobial peptides: dimerization effects and encapsulation in NRLb biomembrane, AP.R

Abstract

A research plan to investigate the biophysical function of viral fusion peptides from HIV and Dengue Virus is described herein. Structure and function in the context of lipid membranes will be studied using synthetic mutagenesis and biophysical measurement. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

CESPEDES, GRAZIELY F.; NOBRE, THATYANE M.; OLIVEIRA, OSVALDO N.; BONG, DENNIS; CILLI, EDUARDO M.. On the role of surrounding regions in the fusion peptide in dengue virus infection. VIROLOGY, v. 557, p. 62-69, MAY 2021. (10/06526-6, 13/50319-3, 18/22214-6, 13/07600-3)