Simultaneous determination of ethinyl estradiol, estradiol, estrone and estriol in wastewater using solid phase extraction with molecularly imprinted polymers (MISPE) by high performance liquid chromatography (HPLC)

• Grant number: 13/12569-8
• Support Opportunities: Regular Research Grants
• Start date: February 01, 2014
• End date: July 31, 2016
• Field of knowledge: Health Sciences - Collective Health - Public Health
• Principal Investigator: Elizabete Campos de Lima
• Grantee: Elizabete Campos de Lima
• Host Institution: Centro de Ciências Naturais e Humanas (CCNH). Universidade Federal do ABC (UFABC). Ministério da Educação (Brasil). Santo André , SP, Brazil

Abstract

Contamination of water resources is one of the main environmental problems of today, and the concern with micropollutants-substances which exist in concentrations in the order of mg L-1 and L-1-ng has increased significantly in recent years because although the low concentration in which they are detected, are capable of causing serious harm to living beings. Among the substances that can be classified as micropollutants stand out hormones. The hormones are estrogens micropollutants that may be harmful to health and environmental damage, so it is necessary to develop techniques to detect and extract these substances from aquatic environments. The impacts triggered by these substances in the environment are considered a matter of global scope and can be observed from the micro invertebrates to large vertebrates. This project aims to develop and optimize a method for extraction and preconcentration on solid phase using MIPs for the determination of hormones estrogen (ethinyl estradiol, estradiol, estrone and estriol) in effluents for subsequent determination and quantification by liquid chromatography DAD and; validate the methodology developed using the protocol Q2R1 ICH. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

VIVIANE DO NASCIMENTO BIANCHI; MARCOS ROBERTO DE ARAUJO SILVA; MARCUS AUGUSTO LAMIM; CLOVIS LUCIO DA SILVA; ELIZABETE CAMPOS DE LIMA. Extração em fase sólida utilizando polímeros de impressão molecular (MISPE) para a determinação de estrógenos em águas superficiais por HPLC. Rev. Ambient. Água, v. 12, n. 3, p. 380-389, 2017-05-00. (13/12569-8)