Quantification of functional abilities in Rett syndrome: a comparison between stages III and IV

• Grant number: 14/00320-8
• Support Opportunities: Regular Research Grants - Publications - Scientific article
• Start date: March 01, 2014
• End date: August 31, 2014
• Field of knowledge: Health Sciences - Medicine - Maternal and Child Health
• Principal Investigator: Carlos Bandeira de Mello Monteiro
• Grantee: Carlos Bandeira de Mello Monteiro
• Host Institution: Faculdade de Saúde Pública (FSP). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

We aimed to evaluate the functional abilities of persons with Rett Syndrome (RTT) in stages III and IV. The group consisted of 60 females, 38 in stage III, mean age (years) of 9.14 with a standard deviation of 5.84 (Min: 2.2 / Max 26.4) and 22 in stage IV, mean age of 12.45 with a standard deviation of 6.17 (Min: 5.3 / Max 26.9), who had been diagnosed with RTT. The evaluation was made using the Pediatric Evaluation of Disability Inventory (PEDI), which has 197 items in the areas of self-care, mobility and social function. The results showed that in the area of self-care, stage III and stage IV, RTT persons had a level of 24.12 and 18.36 (p = 0.002), respectively. In the area of mobility, stage III had 37.22 and stage IV had 14.64 (p < 0.001), while in the area of social function, stage III had 17.72 and stage IV 12.14 (p = 0.016). In conclusion, although persons with stage III RTT have better functional abilities when compared with stage IV, the areas of mobility, self care and social function are quite committed, which shows a great functional dependency and need for help in basic activities of daily lives. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MONTEIRO, CARLOS B. M.; SAVELSBERGH, GEERT J. P.; SMORENBURG, ANA R. P.; GRACIANI, ZODJA; TORRIANI-PASIN, CAMILA; DE ABREU, LUIZ CARLOS; VALENTI, VITOR E.; KOK, FERNANDO. Quantification of functional abilities in Rett syndrome: a comparison between stages III and IV. NEUROPSYCHIATRIC DISEASE AND TREATMENT, v. 10, p. 1213-1222, 2014. (14/00320-8)