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Evaluation of pain and anesthetic efficacy after topical application of microneedles: a randomized clinical trial


This current proposal aims to evaluate the feasibility of microneedles (MNs) as a drug delivery device at the oral mucosa to enable topical anesthesia. In Dentistry, topical anesthesia is performed prior to deep injection of local anesthesia. However, due (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
SANTOS, STEPHANY DI CARLA; FAVARO-MOREIRA, NADIA CRISTINA; ABDALLA, HENRIQUE BALLASSIN; XAVIER AUGUSTO, GABRIELA GAMA; COSTA, YURI MARTINS; VOLPATO, MARIA CRISTINA; GROPPO, FRANCISCO CARLOS; GILL, HARVINDER SINGH; FRANZ-MONTAN, MICHELLE. A crossover clinical study to evaluate pain intensity from microneedle insertion in different parts of the oral cavity. International Journal of Pharmaceutics, v. 592, . (16/24057-0, 12/06974-4, 15/50004-8)

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