An integrative analysis of protein kinases in childhood acute lymphoblastic leukemia

• Grant number: 15/50024-9
• Support Opportunities: Regular Research Grants
• Start date: August 01, 2015
• End date: July 31, 2017
• Field of knowledge: Biological Sciences - Biochemistry - Molecular Biology
• Agreement: UNC Charlotte
• Mobility Program: SPRINT - Projetos de pesquisa - Mobilidade
• Principal Investigator: Paulo Arruda
• Grantee: Paulo Arruda
• Principal researcher abroad: Xinghua Shi
• Institution abroad: University of North Carolina at Charlotte (UNCC), United States
• Host Institution: Instituto de Biologia (IB). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated research grant: 13/50724-5 - Protein Kinase Chemical Biology Center: supporting drug development through open-access research, AP.PITE

Abstract

In this study, we plan to combine complementary expertise from three research teams to develop a comprehensive characterization of PK pathway activation in BCR-ABL1-like ALL, with a goal of identifying and validating new targets for the development of dru (AU)