Complete genome of an atypical DENV2 lineage isolated in Brazil

• Grant number: 15/14591-6
• Support Opportunities: Regular Research Grants - Publications - Scientific article
• Start date: October 01, 2015
• End date: March 31, 2016
• Field of knowledge: Biological Sciences - Biochemistry - Molecular Biology
• Principal Investigator: Camila Malta Romano
• Grantee: Camila Malta Romano
• Host Institution: Instituto de Medicina Tropical de São Paulo (IMT). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

Here we report the complete polyprotein sequence of a Dengue 2 strain isolated in Brazil. This virus belong to the American genotype and has the ability to cause neurovirulence in immunocompetent adult mice. The data presented here may help to the understanding of the genetic determinants responsible for neurovirulence. (AU)