Advanced search
Start date

Contact with Fluoride-Releasing Restorative Materials Can Arrest Simulated Approximal Caries Lesion

Grant number: 15/18100-7
Support Opportunities:Regular Research Grants - Publications - Scientific article
Duration: October 01, 2015 - March 31, 2016
Field of knowledge:Health Sciences - Dentistry - Pediatric Dentistry
Principal Investigator:Daniela Prócida Raggio
Grantee:Daniela Prócida Raggio
Host Institution: Faculdade de Odontologia (FO). Universidade de São Paulo (USP). São Paulo , SP, Brazil


Previous studies have suggested that the presence of white-spot lesion is very probable when adjacent surface is affected by cavitatedlesions. This study evaluated the potential of different fluoride-releasing restorativematerials in arresting enamel white-spot lesionsin approximal contact with them, in vitro (I) and in situ (II). White-spot lesions were formed in 120 primary enamel specimens viapH-cycling.They were put in contact with cylindrical blocks of 6 materials ( n = 20): composite resin, 2 high-viscous glass ionomercements (HVGIC), resin-modified GIC, resin-modified nanoionomer, and polyacid-modified resin. These settings were designedto simulate the contact point between the restoration and simulated approximal lesion. For study I, they were subjected to a newpH-cycling cariogenic challenge for 7 or 14 days (n = 10). For study II, a randomized double-blind in situ design was conducted intwo phases (7/14 days) to promote cariogenic challenge. At the end of both studies, specimens were collected for mineral analysisby cross-sectional microhardness. Higher mineral loss was observed for lesions in contact with resin (p < 0.001). HVGICs were themost efficient in preventing mineral loss, whereas other materials presented an intermediate behavior. It is concluded that fluoride releasing materials can moderately reduce white-spot lesions progression, and HVGIC can arrest enamel lesion when in approximalcontact. (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
Articles published in other media outlets (0 total):
More itemsLess items

Please report errors in scientific publications list using this form.