Mortality from tuberculosis and its relationship with social inequalities : a multicenter study

• Grant number: 15/17586-3
• Support Opportunities: Regular Research Grants
• Duration: June 01, 2016 - May 31, 2018
• Field of knowledge: Health Sciences - Nursing - Public Health Nursing
• Principal Investigator: Ricardo Alexandre Arcêncio
• Grantee: Ricardo Alexandre Arcêncio
• Host Institution: Escola de Enfermagem de Ribeirão Preto (EERP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Associated researchers: Ione Carvalho Pinto ; Marcelino Santos Neto

Abstract

This research project aims to analyze the spatial relationship between tuberculosis mortality and social indicators in the municipalities of Ribeirão Preto - SP , Natal - RN, Sao Luis - MA , Manaus - AM and Londrina - PR . It is an ecological study in which the cases of deaths will be considered in urban areas of the municipalities of Ribeirão Preto, Natal, São Luís, Manaus e Londrina, which is available in the Mortality Information System. Initially it will be performed univariate analysis of demographic and operational variables of the investigated deaths. For the formulation of social indicators will be used the principal component analysis , and selected data of the weighting áreas of São Luís and the areas covered by the municipalities of Ribeirão Preto, Natal, Manaus e Londrina, and considering the Demographic Census 2010. It will use the Multiple linear regression , the least squares method and spatial regression for analysis of the spatial relationship of dependence between social indicators and death rates . The autocorrelation of multiple linear regression will be tested through Global Moran Test. Geocoding of deaths will be processed in TerraView version 4.2.2 , also being considered in the analysis Arcgis - version 10.1 software, Statistica version 12.0 , OpenGeoDa version 1.0. For the diagnosis of the better spatial regression model, it will be used the Lagrange Multiplier test. In all tests , it will set the significance level alpha of 5 % (p < 0.05). The study will be submitted to a Research Ethics Committee , according to the guidelines of the National Health Council Resolution 196/96. The results of this study could be helpful in advancing the knowledge that mortality from tuberculosis is a socially determined event, so the areas identified in the study should be prioritized in terms of investment in public policy and social protection. (AU)

Scientific publications

(12)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ALVES, JOSILENE D.; CHIARAVALLOTI-NETO, FRANCISCO; ARROYO, LUIZ H.; ARCOVERDE, MARCOS A. M.; SANTOS, DANIELLE T.; BERRA, THAIS Z.; ALVES, LUANA S.; RAMOS, ANTONIO C., V; CAMPOY, LAURA T.; BELCHIOR, AYLANA S.; et al. Bayesian spatio-temporal models for mapping TB mortality risk and its relationship with social inequities in a region from Brazilian Legal Amazon. Transactions of the Royal Society of Tropical Medicine and Hygiene, v. 114, n. 5, p. 9-pg., 2020-05-01. (15/17586-3)

BERRA, THAIS ZAMBONI; REGO DE QUEIROZ, ANA ANGELICA; YAMAMURA, MELLINA; ARROYO, LUIZ HENRIQUE; DA CUNHA GARCIA, MARIA CONCEBIDA; POPOLIN, MARCELA PASCHOAL; DOS SANTOS, DANIELLE TALITA; VIEIRA RAMOS, ANTONIO CARLOS; ALVES, LUANA SELES; FRONTEIRA, INES ESTEVINHO; et al. Spatial risk of tuberculosis mortality and social vulnerability in Northeast Brazil. Revista da Sociedade Brasileira de Medicina Tropical, v. 50, n. 5, p. 693-697, SEP-OCT 2017. (15/17586-3)

YAMAMURA, MELLINA; SANTOS NETO, MARCELINO; CHIARAVALLOTI NETO, FRANCISCO; ARROYO, LUIZ HENRIQUE; VIEIRA RAMOS, ANTONIO CARLOS; REGO DE QUEIROZ, ANA ANGELICA; BELCHIOR, AYLANA DE SOUZA; DOS SANTOS, DANIELLE TALITA; CRISPIM, JULIANE DE ALMEIDA; PINTO, IONE CARVALHO; et al. Areas with evidence of equity and their progress on mortality from tuberculosis in an endemic municipality of southeast Brazil. INFECTIOUS DISEASES OF POVERTY, v. 6, OCT 12 2017. (11/22834-5, 15/17586-3)

ANA ANGÉLICA RÊGO DE QUEIROZ; THAÍS ZAMBONI BERRA; MARIA CONCEBIDA DA CUNHA GARCIA; MARCELA PASCHOAL POPOLIN; AYLANA DE SOUZA BELCHIOR; MELLINA YAMAMURA; DANIELLE TALITA DOS SANTOS; LUIZ HENRIQUE ARROYO; RICARDO ALEXANDRE ARCÊNCIO. Padrão espacial e tendência temporal da mortalidade por tuberculose. Revista Latino-Americana de Enfermagem, v. 26, 2018-05-07. (15/17586-3)

REGO QUEIROZ, ANA ANGELICA; BERRA, THAIS ZAMBONI; INOMATA BRUCE, ALEXANDRE TADASHI; DA CUNHA GARCIA, MARIA CONCEBIDA; DOS SANTOS, DANIELLE TALITA; MORAES ARCOVERDE, MARCOS AUGUSTO; ALVES, LUANA SELES; YAMAMURA, MELLINA; SCATENA VILLA, TEREZA CRISTINA; PALHA, PEDRO FREDEMIR; et al. Effect of social development in reducing tuberculosis mortality In northeastern Brazil areas. JOURNAL OF INFECTION IN DEVELOPING COUNTRIES, v. 14, n. 8, p. 11-pg., 2020-08-01. (15/17586-3)

DOS SANTOS, DANIELLE TALITA; ARROYO, LUIZ HENRIQUE; ALVES, YAN MATHIAS; ALVES, LUANA SELES; BERRA, THAIS ZAMBONI; CRISPIM, JULIANE DE ALMEIDA; ALVES, JOSILENE DALIA; RAMOS, DENISSE ANDREA CARTAGENA; ALONSO, JONAS BODINI; DE ASSIS, IVANELIZA SIMIONATO; et al. Survival time among patients who were diagnosed with tuberculosis, the precocious deaths and associated factors in southern Brazil. TROPICAL MEDICINE AND HEALTH, v. 49, n. 1, p. 14-pg., 2021-04-21. (15/17586-3)

LAURA TERENCIANI CAMPOY; LUIZ HENRIQUE ARROYO; ANTÔNIO CARLOS VIEIRA RAMOS; RUBIA LAINE DE PAULA ANDRADE; MARCOS AUGUSTO MORAES ARCOVERDE; JOSILENE DÁLIA ALVES; RICARDO ALEXANDRE ARCÊNCIO. COBERTURA DE TRATAMENTO DIRETAMENTE OBSERVADO SEGUNDO O RISCO DE COINFECÇÃO TB/HIV E DESFECHOSDESFAVORÁVEIS. Cogitare enferm., v. 24, 2019-12-13. (15/17586-3)

DOS SANTOS, DANIELLE TALITA; ALVES, LUANA SELES; MORAES ARCOVERDE, MARCOS AUGUSTO; ARROYO, LUIZ HENRIQUE; BERRA, THAIS ZAMBONI; VIEIRA RAMOS, ANTONIO CARLOS; DOS SANTOS, FELIPE LIMA; ARCENCIO, RICARDO ALEXANDRE; NUNES, CARLA. Social risk and its association with tuberculosis mortality in a context of high inequality in South Brazil: A geo-epidemiology analysis. JOURNAL OF INFECTION AND PUBLIC HEALTH, v. 13, n. 8, p. 1148-1155, AUG 2020. (15/17586-3)

RICARDO ALEXANDRE ARCÊNCIO; AYLANA DE SOUZA BELCHIOR; LUIZ HENRIQUE ARROYO; ALEXANDRE TADASHI INOMATA BRUCE; FELIPE LIMA DOS SANTOS; MELLINA YAMAMURA; ANA ANGÉLICA RÊGO DE QUEIROZ; DANIELLE TALITA DOS SANTOS; SEVERINA ALICE DA COSTA UCHÔA; CARLA NUNES. Distribuição e dependência espacial da mortalidade por tuberculose em um município da região amazônica. Cad. saúde colet., 2022-04-27. (15/17586-3)

DE ASSIS, IVANELIZA SIMIONATO; BERRA, THAIS ZAMBONI; ALVES, LUANA SELES; RAMOS, ANTONIO CARLOS VIERA; ARROYO, LUIZ HENRIQUE; DOS SANTOS, DANIELLE TALITA; ARCOVERDE, MARCOS AUGUSTO MORAES; ALVES, JOSILENE DALIA; DE ALMEIDA CRISPIM, JULIANE; PIERI, FLAVIA MENEGUETTI; et al. Leprosy in urban space, areas of risk for disability and worsening of this health condition in Foz Do Iguacu, the border region between Brazil, Paraguay and Argentina. BMC PUBLIC HEALTH, v. 20, n. 1, JAN 29 2020. (15/17586-3)

ALVES, LUANA SELES; DOS SANTOS, DANIELLE TALITA; MORAES ARCOVERDE, MARCOS AUGUSTO; BERRA, THAIS ZAMBONI; ARROYO, LUIZ HENRIQUE; VIEIRA RAMOS, ANTONIO CARLOS; DE ASSIS, IVANELIZA SIMIONATO; REGO DE QUEIROZ, ANA ANGELICA; ALONSO, JONAS BOLDINI; ALVES, JOSILENE DALIA; et al. Detection of risk clusters for deaths due to tuberculosis specifically in areas of southern Brazil where the disease was supposedly a non-problem. BMC INFECTIOUS DISEASES, v. 19, JUL 17 2019. (15/17586-3)

RICARDO ALEXANDRE ARCÊNCIO; AYLANA DE SOUZA BELCHIOR; LUIZ HENRIQUE ARROYO; ALEXANDRE TADASHI INOMATA BRUCE; FELIPE LIMA DOS SANTOS; MELLINA YAMAMURA; ANA ANGÉLICA RÊGO DE QUEIROZ; DANIELLE TALITA DOS SANTOS; SEVERINA ALICE DA COSTA UCHÔA; CARLA NUNES. Distribuição e dependência espacial da mortalidade por tuberculose em um município da região amazônica. Cad. saúde colet., v. 30, n. 1, p. 1-12, 2022-04-27. (15/17586-3)