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Design of selective inhibitors of glycoside hydrolase (OGA) using chemoinformatic tools

Grant number: 15/26885-4
Support Opportunities:Research Grants - Visiting Researcher Grant - International
Duration: November 15, 2016 - December 14, 2016
Field of knowledge:Health Sciences - Pharmacy
Principal Investigator:Ivone Carvalho
Grantee:Ivone Carvalho
Visiting researcher: Nuria Eugenia Campillo
Visiting researcher institution: Consejo Superior de Investigaciones Científicas (CSIC), Spain
Host Institution: Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil


The Prof. Campillo visit will allow the development of a new work proposal to identify OGA inhibitors, an important target involved in Alzheimer's disease, using libraries of compounds from the visitor's Research Institute, CSIC. The results will allow the Brazilian group to continue the project, such as the synthesis of derivatives previously identified by screening and biological assays. (AU)

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