EFFECT OF CAVITY GEOMETRY OF NON CARIOUS CERVICAL LESIONS AND TYPE OF RESIN COMPOSITE ON RESTORATIVE SUCCESS RATE - IN VITRO, IN SILICO, AND IN VIVO OBSERVATIONS, AND SYSTEMATIC REVIEW

• Grant number: 16/14429-7
• Support Opportunities: Regular Research Grants
• Start date: October 01, 2016
• End date: September 30, 2018
• Field of knowledge: Health Sciences - Dentistry - Dental Clinics
• Principal Investigator: Taciana Marco Ferraz Caneppele
• Grantee: Taciana Marco Ferraz Caneppele
• Host Institution: Instituto de Ciência e Tecnologia (ICT). Universidade Estadual Paulista (UNESP). Campus de São José dos Campos. São José dos Campos , SP, Brazil
• Associated researchers: Alessandra Buhler Borges ; Alexandre Luiz Souto Borges ; Eduardo Bresciani

Abstract

Objectives: This project involves a systematic review, in vitro, in silico studies, and a randomized clinical trial in order to understand the role of geometry cavity of non-carious cervical lesions (NCCL) on longevity of restorations, and evaluate the effectiveness of the use of resins type "bulk-fill" in this type of lesion. Methods: Systematic review: It will searched the main electronic databases with the defined search strategy according to the research question and PICO strategy (P): Adult patients with non-carious cervical lesions; (I) Intervention: Big size NCCL restorations; (C) Comparison: Small size NCCL restorations; (O) Outcome: Success rate. It will be eligible only randomized clinical trials with at least 18 months of follow-up. In the included studies an analysis of risk of bias will be performed. Laboratorial studies: In vitro: Sixty bovine incisors will be divided into 2 groups according to the extent of class V cavity to be prepared: large Extension or small extension. Each group will be divided into two subgroups, according to the restorative material: Filtek Bulk Fill (3MEspe) or Filtek Z350 (3MEspe). The marginal gaps will be analyzed in stereomicroscope before and after 15,000 cycles of thermal cycling. In silico: The same cavity geometries carried out in bovine teeth will be drawn on computer, for finite element analysis, in order to analyze the tensions generated by the polymerization shrinkage. Randomized clinical trial: Volunteers will receive restorations class V type in non-carious cervical lesions previously graded by the extent of the cavity in cervical-occlusal direction. The restorations will be performed, according to the division of groups with conventional resin composite or resin type "bulk-fill". The success rate will be assessed after 6, 12 and 18 months. The data will be analyzed statistically. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

CORREIA, A. M. O.; JUREMA, A. L. B.; ANDRADE, M. R.; BORGES, A. L. S.; BRESCIANI, E.; CANEPPELE, T. M. F.. Clinical Evaluation of Noncarious Cervical Lesions of Different Extensions Restored With Bulk-fill or Conventional Resin Composite: Preliminary Results of a Randomized Clinical Trial. Operative Dentistry, v. 45, n. 1, p. E11-E20, JAN-FEB 2020. (16/14429-7)

CORREIA, A. M. O.; BRESCIANI, E.; BORGES, A. B.; PEREIRA, D. M.; MAIA, L. C.; CANEPPELE, T. M. F.. Do Tooth- and Cavity-related Aspects of Noncarious Cervical Lesions Affect the Retention of Resin Composite Restorations in Adults? A Systematic Review and Meta-analysis. Operative Dentistry, v. 45, n. 3, p. E124-E140, MAY-JUN 2020. (16/14429-7)