Fabrication and characterization of peptide-polymer hybrid hydrogels for bioanalytical applications

• Grant number: 16/50188-4
• Support Opportunities: Regular Research Grants
• Start date: September 01, 2016
• End date: October 31, 2018
• Field of knowledge: Physical Sciences and Mathematics - Chemistry
• Agreement: University of Melbourne
• Mobility Program: SPRINT - Projetos de pesquisa - Mobilidade
• Principal Investigator: Wendel Andrade Alves
• Grantee: Wendel Andrade Alves
• Principal researcher abroad: Francesca Cavalieri
• Institution abroad: University of Melbourne, Australia
• Host Institution: Centro de Ciências Naturais e Humanas (CCNH). Universidade Federal do ABC (UFABC). Ministério da Educação (Brasil). Santo André , SP, Brazil
• Associated research grant: 15/24018-1 - Polymer-Peptide Conjugates for hydrogel formulation and its usage in detection, AP.R

Abstract

The objective of this research project is to promote an exchange program between UoM and UFABC. The proposed joint project is set to enhance educational/research scientific excellence in the two universities. This will ultimately help in securing large grants from other organizations for continuing our collaborative research activities for the long-term. The achievement of this goal requires an interdisciplinary approach based on complementary expertise of the two participants in peptide self-assembly and polymeric hydrogels. The outcome of this collaborative project will yield high quality publications and breakthrough for rapid diagnostic of leishmaniosis and other diseases endemic in tropical countries. The objective of this research/exchange project is to fabricate a new biosensor based on peptidepolymer hydrogels for the detection of leishmaniosis and other diseases endemic in tropical countries. The achievement of this goal requires an interdisciplinary approach based on complementary expertise of the two participants. Prof. Alves is an expert in peptide synthesis and self-assembly into nanostructures whereas Dr. Cavalieri has consolidated skins on the engineering and characterization of polymer based hydrogels for biomedical applications. The proposed joint research project aligns well with the ongoing research of the participants and meantime increases skills and knowledge of both applicants. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

GERBELLI, BARBARA B.; VASSILIADES, SANDRA V.; ROJAS, JOSE E. U.; PELIN, JULIANE N. B. D.; MANCINI, RODRIGO S. N.; PEREIRA, WALLACE S. G.; AGUILAR, ANDREA M.; VENANZI, MARIANO; CAVALIERI, FRANCESCA; GIUNTINI, FRANCESCA; et al. Hierarchical Self-Assembly of Peptides and its Applications in Bionanotechnology. MACROMOLECULAR CHEMISTRY AND PHYSICS, v. 220, n. 14, p. 22-pg., 2019-07-01. (18/05888-3, 17/02317-2, 14/50867-3, 16/50188-4, 14/50972-1)

GERBELLI, BARBARA B.; VASSILIADES, SANDRA V.; ROJAS, JOSE E. U.; PELIN, JULIANE N. B. D.; MANCINI, RODRIGO S. N.; PEREIRA, WALLACE S. G.; AGUILAR, ANDREA M.; VENANZI, MARIANO; CAVALIERI, FRANCESCA; GIUNTINI, FRANCESCA; et al. Hierarchical Self-Assembly of Peptides and its Applications in Bionanotechnology. MACROMOLECULAR CHEMISTRY AND PHYSICS, v. 220, n. 14, SI, JUL 2019. (18/05888-3, 16/50188-4, 17/02317-2, 14/50972-1, 14/50867-3)

LIBERATO, MICHELLE S.; MANCINI, RODRIGO S. N.; FACTORI, IRINA M.; FERREIRA, FABIO F.; DE OLIVEIRA, VIVIAN L.; CARNIELLI, JULIANA B. T.; GUHA, SUCHISMITA; PERONI, LUIS A.; OLIVEIRA, MARCONE A. L.; ALVES, WENDEL A.. Peptide-Based Assemblies on Electrospun Polyamide-6/Chitosan Nanofibers for Detecting Visceral Leishmaniasis Antibodies. ACS APPLIED ELECTRONIC MATERIALS, v. 1, n. 10, p. 2086-2095, OCT 2019. (14/50867-3, 17/02317-2, 16/50188-4)