Clinical findings among progestin-only contraceptives' users

• Grant number: 15/20504-9
• Support Opportunities: Research Projects - Thematic Grants
• Start date: November 01, 2016
• End date: October 31, 2023
• Field of knowledge: Health Sciences - Medicine - Maternal and Child Health
• Principal Investigator: Luis Guillermo Bahamondes
• Grantee: Luis Guillermo Bahamondes
• Host Institution: Centro de Atenção Integral à Saúde da Mulher (CAISM). Hospital da Mulher Professor Doutor José Aristodemo Pinotti. Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Pesquisadores principais: Arlete Maria dos Santos Fernandes ; Carolina Sales Vieira ; Cássia Raquel Teatin Juliato ; Ilza Maria Urbano Monteiro
• Associated scholarship(s): 21/01160-8 - Evaluate various clinical aspects of the use of Levonorgestrel intrauterine system 52MG (SIU-LNG), BP.IC; 20/14899-9 - Evaluating various clinical aspects of the use of levonorgestrel intrauterine system 52mg (SIU-LNG), BP.IC; 18/18323-4 - Use of levonorgestrel-releasing intrauterine system in women using oral anticoagulants, BP.IC; 17/05302-6 - Eating behavior and quality of life in young women from the exchange of contraceptive method for long-acting reversible methods up to 12 months post admission, BP.PD; 17/08595-4 - Use of levonorgestrel-releasing IUD in women submitted to solid organ transplantation, BP.IC

Abstract

The Family Planning clinic of the UNICAMP brings together researchers with solid experience in teaching, research and assistance in Gynecology and Reproductive Medicine in Brazil and has national and international recognition for implementing a joint proposal for research and development, which translates into real benefits for the science and for the country. This study group has extensive experience in research on contraception, especially devoted to research on long-acting reversible contraceptives (LARCs), not only in use for contraception but also to the benefits in treating diseases. Therefore, our research line cover different stages of the female reproductive life cycle and prevalent medical conditions and have in common the influence of these different contraceptive methods to metabolism, bleeding disorders, lifestyle, and satisfaction. This line of research reflects an intense and productive activity regarding to the potential for incorporation of substantial advances in the health science and knowledge in reproductive medicine, but also in future transformation of the results obtained in regional policies to promote women's health. Therefore, it is important to note that in addition to the scientific research, population-based studies, projects directly linked to public agencies of health, research on populations susceptible as women with abnormal bleeding, diseases such as lupus, osteoporosis, among others, will allow greater dialogue with the public sector and society. (AU)

Scientific publications

(35)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

LAPORTE, MONTAS; METELUS, SHERLY; ALI, MOAZZAM; BAHAMONDES, LUIS. ajor differences in the characteristics of users of the copper intrauterine device or levonorgestrel intrauterine system at a clinic in Campinas, Brazi. International Journal of Gynecology & Obstetrics, v. 156, n. 2, p. 240-246, FEB 2022. (15/20504-9)

CONZ, LIVIA; MOTA, BRUNA SALANI; BAHAMONDES, LUIS; DORIA, MAIRA TEIXEIRA; MAURICETTE DERCHAIN, SOPHIE FRANCOISE; RIEIRA, RACHEL; SARIAN, LUIS OTAVIO. Levonorgestrel-releasing intrauterine system and breast cancer risk: A systematic review and meta-analysis. ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, v. 99, n. 8, FEB 2020. (15/20504-9)

MARGATHO, DEBORAH; CARVALHO, NELSILENE MOTA; ELOY, LARISSA; BAHAMONDES, LUIS. Assessment of biomarkers in women with endometriosis-associated pain using the ENG contraceptive implant or the 52 mg LNG-IUS: a non-inferiority randomised clinical trial. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, v. 23, n. 5, p. 344-350, 2018. (15/20504-9)

BAHAMONDES, LUIS; MONTEIRO, ILZA; FERNANDES, ARLETE; GAFFIELD, MARY E.. Follow-up visits to check strings after intrauterine contraceptive placement cannot predict or prevent future expulsion. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, v. 24, n. 2, p. 97-101, MAR 4 2019. (15/20504-9)

LAPORTE, MONTAS; MARANGONI, JR., MARCOS; SURITA, FERNANDA; JULIATO, CASSIA T.; MIADAIRA, MARIANA; BAHAMONDES, LUIS. Postplacental placement of intrauterine devices: A randomized clinical trial. Contraception, v. 101, n. 3, p. 153-158, MAR 2020. (15/20504-9)

JULIATO, CASSIA R. T.; STAHLSCHMIDT, PAULO; FERNANDES, ARLETE; MONTEIRO, ILZA; BAHAMONDES, LUIS. A case series on the use of levonorgestrel 52 mg intrauterine system after OF organ transplant. Contraception, v. 98, n. 3, p. 252-254, SEP 2018. (15/20504-9)

P. SILVA; S. QADIR; A. FERNANDES; L. BAHAMONDES; J.F. PEIPERT. Dietary intake and eating behavior in depot medroxyprogesterone acetate users: a systematic review. Brazilian Journal of Medical and Biological Research, v. 51, n. 6, 2018-04-23. (09/53293-0, 15/20504-9)

MARGATHO, DEBORAH; MAKUCH, MARIA Y.; BAHAMONDES, LUIS. Experiences of male partners of women with endometriosis-associated pelvic pain: a qualitative study. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, v. 27, n. 6, p. 7-pg., 2022-07-22. (15/20504-9)

GOMEZ-ELIAS, MATIAS D.; MAY, MARIA; MUNUCE, MARIA JOSE; BAHAMONDES, LUIS; CUASNICU, PATRICIA S.; COHEN, DEBORA J.. A single post-ovulatory dose of ulipristal acetate impairs post-fertilization events in mice. MOLECULAR HUMAN REPRODUCTION, v. 25, n. 5, p. 257-264, MAY 2019. (15/20504-9)

BAHAMONDES, LUIS; MAKUCH, MARIA Y.. Awareness of the non-contraceptive benefits of reversible contraceptive methods in a cohort of Brazilian women: an exploratory study. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, v. N/A, p. 6-pg., 2022-04-04. (15/20504-9)

CARVALHO, NELSILENE M.; CHOU, VICTORIA; MODESTO, WALESKA; MARGATHO, DEBORAH; GARCIA, ELAINE A. L.; BAHAMONDES, LUIS. Relationship between user satisfaction with the levonorgestrel-releasing intrauterine system and bleeding patterns. JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, v. 43, n. 11, p. 1732-1737, NOV 2017. (15/20504-9)

BAHAMONDES, LUIS; ALI, MOAZZAM; MONTEIRO, ILZA; FERNANDES, ARLETE. Stagnant contraceptive sales after the Zika epidemic in Brazil. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, v. 22, n. 5, p. 381-383, 2017. (15/20504-9)

MELHADO-KIMURA, VANESKA; ANNICHINO BIZZACCHI, JOYCE MARIA; PICOLI QUAINO, SUSAN KELLY; MONTALVAO, SILMARA; BAHAMONDES, LUIS; FERNANDES, ARLETE. Effect of the injectable contraceptive depot-medroxyprogesterone acetate on coagulation parameters in new users. JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, v. 43, n. 6, p. 1054-1060, JUN 2017. (11/14827-9, 15/20504-9)

DE NADAI, MARIANE N.; VIEIRA, CAROLINA S.; MONTEIRO, ILZA M. U.; JULIATO, CASSIA R. T.; FRANCESCHINI, S. A.; YAMAGUTI, E. M. M.; BRAGA, G. C.; BAHAMONDES, L.. Practical training of health care providers in insertion of contraceptive implants: findings from two Brazilian centres. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, v. 26, n. 6, p. 499-502, NOV 2 2021. (15/20504-9)

LOPES-GARCIA, ELAINE A.; CARMONA, ELENICE V.; MONTEIRO, ILZA; BAHAMONDES, LUIS. Assessment of pain and ease of intrauterine device placement according to type of device, parity, and mode of delivery. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, v. 28, n. 3, p. 5-pg., 2023-03-24. (15/20504-9)

MARANGONI, JR., MARCOS; LAPORTE, MONTAS; SURITA, FERNANDA; KRAFT, MARIA B.; BAHAMONDES, LUIS; JULIATO, CASSIA R. T.. One-year follow up on post-placental IUD insertion: A randomized clinical trial. ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, v. 100, n. 4, MAR 2021. (15/20504-9)

CHARLES, CHARLES M'POCA; MUNEZERO, ALINE; BAHAMONDES, LUIS G.; PACAGNELLA, RODOLFO C.. Comparison of contraceptive sales before and during the COVID-19 pandemic in Brazil. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, v. 27, n. 2, p. 6-pg., 2022-02-11. (15/20504-9)

VERSAILLES, JACQUES B. E.; METELUS, SHERLY; PELOGGIA, ALESSANDRA; LAPORTE, MONTAS; BAHAMONDES, LUIS; JULIATO, CASSIA. Women's perspectives on impact on the post menopause of use of the 52 mg levonorgestrel intrauterine device during the menopausal transition. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, v. 28, n. 4, p. 3-pg., 2023-05-27. (15/20504-9)

DE NADAI, MARIANE N.; VIEIRA, CAROLINA S.; MONTEIRO, ILZA M. U.; JULIATO, CASSIA R. T.; FRANCESCHINI, S. A.; YAMAGUTI, E. M. M.; BRAGA, G. C.; BAHAMONDES, L.. Practical training of health care providers in insertion of contraceptive implants: findings from two Brazilian centres. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, JUN 2021. (15/20504-9)

LAURA MIRANDA; MARIA HELENA DE SOUSA; ANIBAL FAUNDES; CÁSSIA JULIATO. Taxas de continuação com o sistema intrauterino de liberação de levonorgestrel de 52mg de acordo com o motivo principal de seu uso. Revista Brasileira de Ginecologia e Obstetrícia, v. 43, n. 4, p. 291-296, 2021-06-18. (15/20504-9)

ZUMOFFEN, CARLOS; GOMEZ-ELIAS, MATIAS D.; CAILLE, ADRIANA M.; BAHAMONDES, LUIS; CUASNICU, PATRICIA S.; COHEN, DEBORA J.; JOSE MUNUCE, MARIA. Study of the effect of ulipristal acetate on human sperm ability to interact with tubal tissue and cumulus-oocyte-complexes. Contraception, v. 95, n. 6, p. 586-591, JUN 2017. (15/20504-9)

BAHAMONDES, LUIS; ALI, MOAZZAM; MONTEIRO, ILZA; FERNANDES, ARLETE. Contraceptive sales in the setting of the Zika virus epidemic. Human Reproduction, v. 32, n. 1, p. 88-93, JAN 2017. (15/20504-9)

MIRANDA, LAURA; DE SOUSA, MARIA HELENA; FAUNDES, ANIBAL; JULIATO, CASSIA. Continuation Rates of the 52-mg Levonorgestrel- releasing Intrauterine System according to the Primary Reason for its Use. Revista Brasileira de Ginecologia e Obstetrícia, v. 43, n. 4, p. 291-296, 2021. (15/20504-9)

MARGATHO, DEBORAH; CARVALHO, NELSILENE MOTA; BAHAMONDES, LUIS. Endometriosis-associated pain scores and biomarkers in users of the etonogestrel-releasing subdermal implant or the 52-mg levonorgestrel-releasing intrauterine system for up to 24 months. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, v. 25, n. 2, FEB 2020. (15/20504-9)

BAHAMONDES, M. VALERIA; BAHAMONDES, LUIS. Intrauterine device use is safe among nulligravidas and adolescent girls. ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, v. 100, n. 4, FEB 2021. (15/20504-9)

LOPES GARCIA, ELAINE APARECIDA; FERREIRA, JESSICA MAYRA; VEIGA-JUNIOR, NELIO; BAHAMONDES, LUIS; MONTEIRO, ILZA. Knowledge, Attitude, and Practices Related to the SARS-CoV-2 Pandemic among Women Seeking Contraceptive Methods. Revista Brasileira de Ginecologia e Obstetrícia, v. 44, n. 04, p. 7-pg., 2022-04-01. (15/20504-9)

MUNUCE, M. J.; JIMENEZ GUERRERO, M.; COTAN, D.; GARCIA, A.; CAILLE, A. M.; CUASNICU, P.; BAHAMONDES, L.; HORCAJADAS, J.; COHEN, D.. Effect of Ulipristal Acetate (UPA) on the gene expression profiling of endometrial cells in culture. Human Reproduction, v. 33, p. 2-pg., 2018-07-01. (15/20504-9)

LUIS BAHAMONDES; ARLETE FERNANDES; ILZA MONTEIRO. Barreiras à implementação e consolidação de um programa de planejamento familiar que atenda às necessidades brasileiras. Revista Brasileira de Ginecologia e Obstetrícia, v. 39, n. 8, p. 373-375, 2017-08-00. (15/20504-9)

JIMENEZ GUERRERO, MARIPAZ; FAVA, MARIANA; BACCARO, LUIZ F.; CAILLE, ADRIANA M.; CUASNICU, PATRICIA S.; HORCAJADAS, JOSE A.; COHEN, DEBORA J.; BAHAMONDES, LUIS; COTAN, DAVID; MUNUCE, MARIA JOSE. Effect of ulipristal acetate on gene expression profile in endometrial cells in culture and in vivo upon post-ovulatory administration in fertile women. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, AUG 2021. (15/20504-9)

FURLANI, REBECA M.; GARCIA, ELAINE; CASTRO, SARA; MACHADO, HELYMAR C.; BAHAMONDES, LUIS; MONTEIRO, ILZA. xpulsion rates of the levonorgestrel 52 mg intrauterine system are similar among women with heavy menstrual bleeding and users for contraceptio. Contraception, v. 105, p. 75-79, JAN 2022. (15/20504-9)

LAPORTE, MONTAS; CHARLES, CHARLES M.; METELUS, SHERLY; PELOGGIA, ALESSANDRA; PAEZ, GABRIELA DE O.; JULIATO, CASSIA T.; BAHAMONDES, LUIS. Reasons reported by women for choosing the levonorgestrel intrauterine system as a contraceptive method. International Journal of Gynecology & Obstetrics, DEC 2021. (15/20504-9)

BRULL, ELIZA; MACHADO, HELYMAR COSTA; BAHAMONDES, LUIS; JULIATO, CASSIA R. T.. Expulsion and continuation rates of the levonorgestrel 52 mg intrauterine system was similar among nulligravid and parous users. International Journal of Gynecology & Obstetrics, NOV 2021. (15/20504-9)

LAPORTE, MONTAS; PELOGGIA, ALESSANDRA; MARCELINO, ANA C.; DE CARVALHO, LARISSA S.; BAHAMONDES, LUIS. Perspectives of health care providers regarding the levonorgestrel-releasing intrauterine system. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, NOV 2021. (15/20504-9)

DA CUNHA PEREIRA, PAULA; MONTEIRO, ILZA; BAHAMONDES, LUIS. Natural contraception apps knowledge among Brazilian women and Obstetrics and Gynaecology residents. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, v. N/A, p. 5-pg., 2022-05-14. (15/20504-9)

MANHICA, SUZANA, I; BAHAMONDES, LUIS; LAPORTE, MONTAS; ANJOS, FABIANA; VISCOLA, MARCO; GARCIA, ELAINE; PAIVA, LUCIA C.. Single-visit long-acting reversible contraception provision and pregnancy rates within 3 months. International Journal of Gynecology & Obstetrics, v. N/A, p. 5-pg., 2022-12-26. (15/20504-9)