Mult-user equipment approved in the grant 2014/50249-8: ultra-performance liquid chromatography with supercritical CO2 and mass detector

• Grant number: 16/20609-8
• Support Opportunities: Multi-user Equipment Program
• Start date: February 01, 2017
• End date: January 31, 2024
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Agreement: GlaxoSmithKline
• Principal Investigator: Arlene Gonçalves Corrêa
• Grantee: Arlene Gonçalves Corrêa
• Host Institution: Centro de Ciências Exatas e de Tecnologia (CCET). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil
• Associated research grant: 14/50249-8 - Green chemistry: sustainable synthetic methods employing benign solvents, safer reagents, and bio-renewable feedstock, AP.PCPE
• EMU web page: http://www.cersuschem.ufscar.br/pesquisa/equipamentos-multiusuario
• Type of equipment: Caracterização de Materiais - Análises Químicas - Cromatografia líquida acoplada a espectrômetro de massa
• Manufacturer: Waters
• Model: Detector Xevo TQD + Cromatografo Fluído Super Crítico ACQUITY UPC2

Abstract

The purchase of this equipment will be of pivotal importance to all members of the CERSusChem to fulfill their basic needs of research, as the proposal aims the preparation, separation and identification of enantiomerically pure or chiral enriched substances. Therefore, we plan to use the ultra-performance liquid chromatography as analytical tool. This new technology provides both high speed and resolution without sacrificing basic parameters of the analysis. A very important characteristic of this system is the rate at which analysis can be executed - this factor will facilitate the identification and characterization of the synthesized compounds by our staff, and thus, the results can be obtained in a quickly and effectively way. Furthermore, we also have to emphasize that this device has, supercritical CO2 as mobile phase in the presence of small amounts of a co-solvent. This feature avoids the need to purchase special solvents, which are generally expensive, being a waste free apparatus - therefore contributing to the principles of green chemistry. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MOREIRA, AILTON. J.; DOS SANTOS, BARBARA R. M.; DIAS, JEFERSON A.; RABELLO, PIETRA T.; COELHO, DYOVANI; MASCARO, LUCIA H.; FRESCHI, GIAN P. G.; GOBATO, YARA G.; GALETI, HELDER V. A.; MASTELARO, VALMOR R.; et al. Photoactivity of boron-or nitrogen-modified TiO2 for organic pollutants degradation: Unveiling the photocatalytic mechanisms and by-products. JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, v. 11, n. 1, p. 12-pg., 2022-12-30. (17/11986-5, 16/20609-8, 13/07296-2)

DE OLIVEIRA, CRISTIANE; RENDA, CARMEM G.; MOREIRA, AILTON J.; PEREIRA, ERNESTO C.; FRESCHI, GIAN P. G.; BERTHOLDO, ROBERTO. Evaluation of a graphitic porous carbon modified with iron oxides for atrazine environmental remediation in water by adsorption. Environmental Research, v. 219, p. 12-pg., 2022-12-20. (16/20609-8, 13/07296-2, 17/11986-5)

MOREIRA, NATAILIA M.; DE MIRANDA, INGRID T.; DOS SANTOS, JHONATHAN R. N.; OPATZ, TILL; OLIVA, GLAUCIUS; GUIDO, RAFAEL V. C.; CORREA, ARLENE G.. Copper-Catalyzed Synthesis of Pyrrolo[1,2-c]quinazolines and Pyrrolo[2,1-a]isoquinolines and Antiplasmodial Evaluation. Journal of Organic Chemistry, v. 88, n. 13, p. 10-pg., 2023-06-05. (16/20609-8, 13/07600-3, 14/50249-8, 17/19940-4, 20/12904-5, 20/10349-4, 22/01066-4)