Histopathology of equine laminar corium submitted to experimental ischemia/intestinal reperfusion in horses

• Grant number: 06/05271-9
• Support Opportunities: Scholarships in Brazil - Master
• Start date: March 01, 2007
• End date: February 28, 2009
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
• Principal Investigator: Carlos Augusto Araújo Valadão
• Grantee: Luciane Maria Laskoski
• Host Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil

Abstract

Equine acute laminitis is a highly debilitating disease of the digital soft tissues. Two main theories regarding its pathophysiology state that blood flow alterations and laminar basement membrane breakdown are involved in the establishment of this severe disease. Laminitis usually occurs secondary to other diseases such as acute gastrointestinal tract disease (colic). The pathophysiology, and therefore the treatment, of equine laminitis has been a source of controversy in the last few years. The purpose this study is to evaluated histological techniques and though the enzymatic measurement the possible alterations caused in the laminar corium during the intestinal ischemia reperfusion injury in horses treated or not with hydrocortisone. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

LUCIANE M. LASKOSKI; ROSANGELA LOCATELLI-DITTRICH; RENATO S. SOUSA; JULIANA S. BRUM; THIERRY G. CRISTO; FABIANO MONTIANI-FERREIRA; OLAIR C. BELTRAME; CARLOS A.A. VALADÃO. Lesões laminares em cavalos com estresse oxidativo sistêmico, acometidos por doenças gastrintestinais experimentalmente induzidas ou de ocorrência natural. Pesquisa Veterinária Brasileira, v. 36, n. 8, p. 694-700, 2016-08-00. (07/01604-6, 06/05271-9)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

LASKOSKI, Luciane Maria. Alterações morfológicas, apoptose e expressão de metaloproteinases no tecido laminar de equinos submetidos à obstrução intestinal experimental: efeitos da hidrocortisona. 2009. Master's Dissertation - Universidade Estadual Paulista (Unesp). Faculdade de Ciências Agrárias e Veterinárias. Jaboticabal Jaboticabal.