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Electroanalytical and chromatographic methods applied in the analysis of mycobacteria and photoeletrocatalytic disinfection of mycobacteria and candidas using electrodes of Ti/TiO2 and Ti/TiO2-Ag nanotubes

Grant number: 09/09403-5
Support Opportunities:Scholarships in Brazil - Doctorate
Effective date (Start): October 01, 2009
Effective date (End): August 31, 2013
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
Principal Investigator:Maria Valnice Boldrin
Grantee:Michelle Fernanda Brugnera
Host Institution: Instituto de Química (IQ). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brazil

Abstract

One of the biggest challenges of the public water supply is to provide drinking water free of microorganisms or pathogens from waste by-products generated during the water treatment. Among the various types of pathogen the inactivation of the mycobacteria has been a challenge, since they present as ambiguous characteristics of biofilm formation in water, to give a huge resistance to conventional treatments and are responsible for a wide range of infections. This project aims to investigate the potential of the technique of photoelectrocatalysis as a method of disinfecting water. To this aim is to develop electrodes for Ti/TiO2 in the form of nanotubes with and without doping with Ag and apply them to treat the type of mycobacteria: M. smegmatis, M. fortuitum, M. Chelonae, M. avium, M. kansasii and M. turberculosis. The performance of the method will be evaluated are testing its effectiveness against the inactivation of mycobacteria under UV and sunlight in the presence of chloride and sulfate as supporting electrolyte monitoring is the kinetic antimycobacterial testing and training of sub-products using conventional analytical chemical methods .

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Scientific publications (7)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
BRUGNERA, MICHELLE FERNANDA; MIYATA, MARCELO; FUJIMURA LEITE, CLARICE QUEICO; BOLDRIN ZANONI, MARIA VALNICE. Silver ion release from electrodes of nanotubes of TiO2 impregnated with Ag nanoparticles applied in photoelectrocatalytic disinfection. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, v. 278, p. 1-8, . (09/09403-5)
BRUGNERA, MICHELLE FERNANDA; MIYATA, MARCELO; ZOCOLO, GUILHERME JULIAO; FUJIMURA LEITE, CLARICE QUEICO; BOLDRIN ZANONI, MARIA VALNICE. A photoelectrocatalytic process that disinfects water contaminated with Mycobacterium kansasii and Mycobacterium avium. WATER RESEARCH, v. 47, n. 17, p. 6596-6605, . (09/09403-5)
PIRES, REGINA H.; BRUGNERA, MICHELLE F.; ZANONI, MARIA VALNICE B.; GIANNINI, MARIA JOSE S. M.. Effectiveness of photoelectrocatalysis treatment for the inactivation of Candida parapsilosis sensu stricto in planktonic cultures and biofilms. APPLIED CATALYSIS A-GENERAL, v. 511, p. 149-155, . (11/12734-3, 09/09403-5, 12/01270-9)
BRUGNERA, MICHELLE FERNANDA; MIYATA, MARCELO; ZOCOLO, GUILHERME JULIAO; FUJIMURA LEITE, CLARICE QUEICO; BOLDRIN ZANONI, MARIA VALNICE. Inactivation and disposal of by-products from Mycobacterium smegmatis by photoelectrocatalytic oxidation using Ti/TiO2-Ag nanotube electrodes. Electrochimica Acta, v. 85, p. 33-41, . (09/09403-5)
BRUGNERA, MICHELLE FERNANDA; MIYATA, MARCELO; FUJIMURA LEITE, CLARICE QUEICO; BOLDRIN ZANONI, MARIA VALNICE. Sensitive Voltammetric Sensor for Fast Detection of Mycolic Acids Present in Mycobacteria. International Journal of Electrochemical Science, v. 8, n. 5, p. 6591-6602, . (09/09403-5)
BRUGNERA, MICHELLE FERNANDA; MIYATA, MARCELO; ZOCOLO, GUILHERME JULIAO; FUJIMURA LEITE, CLARICE QUEICO; BOLDRIN ZANONI, MARIA VALNICE. Ti/TiO2 nanotubes enhance Mycobacterium fortuitum, Mycobacterium chelonae and Mycobacterium abscessus inactivation in water. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, v. 89, n. 11, p. 1686-1696, . (09/09403-5)
BRUGNERA, MICHELLE FERNANDA; MIYATA, MARCELO; ZOCOLO, GUILHERME JULIAO; GONSALVES TESSARO, LETICIA LOUIZE; FUJIMURA LEITE, CLARICE QUEICO; BOLDRIN ZANONI, MARIA VALNICE. A promising technology based on photoelectrocatalysis against Mycobacterium tuberculosis in water disinfection. ENVIRONMENTAL TECHNOLOGY, v. 42, n. 5, p. 743-752, . (09/09403-5)

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