Study of the regulation of recombinant ADAM-17 by determining phosphorylation sites of the cytoplasmic domain and its ligands in normal and cancer cells.

• Grant number: 09/18301-1
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: May 01, 2010
• End date: April 30, 2013
• Field of knowledge: Biological Sciences - Biochemistry - Chemistry of Macromolecules
• Principal Investigator: Adriana Franco Paes Leme
• Grantee: Annelize Zambon Barbosa Aragão
• Host Institution: Centro Nacional de Pesquisa em Energia e Materiais (CNPEM). Ministério da Ciência, Tecnologia e Inovação (Brasil). Campinas , SP, Brazil

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ARAGAO, ANNELIZE Z. B.; BELLONI, MARILIA; SIMABUCO, FERNANDO M.; ZANETTI, MARIANA R.; YOKOO, SAMI; DOMINGUES, ROMENIA R.; KAWAHARA, REBECA; PAULETTI, BIANCA A.; GONCALVES, ANDERSON; AGOSTINI, MICHELLE; et al. Novel Processed Form of Syndecan-1 Shed from SCC-9 Cells Plays a Role in Cell Migration. PLoS One, v. 7, n. 8, AUG 15 2012. (10/09642-7, 10/19278-0, 09/18301-1)

ARAGAO, ANNELIZE Z. B.; NOGUEIRA, MARIA LUIZA C.; GRANATO, DANIELA C.; SIMABUCO, FERNANDO M.; HONORATO, RODRIGO V.; HOFFMAN, ZAIRA; YOKOO, SAMI; LAURINDO, FRANCISCO R. M.; SQUINA, FABIO M.; ZERI, ANA CAROLINA M.; et al. Identification of Novel Interaction between ADAM17 (a Disintegrin and Metalloprotease 17) and Thioredoxin-1. Journal of Biological Chemistry, v. 287, n. 51, p. 43071-43082, DEC 14 2012. (11/02267-9, 09/54067-3, 10/19278-0, 10/15675-5, 09/18301-1)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

ARAGÃO, Annelize Zambon Barbosa. Thioredoxin-1 is a novel ligand of ADAM17 cytoplasmic domain and participates in its modulation. 2014. Doctoral Thesis - Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia Campinas, SP.