Vascular effects of the treatment with conjugated equine estrogens associated with testosterone in female spontaneously hypertensive rats.

• Grant number: 10/03608-1
• Support Opportunities: Scholarships in Brazil - Master
• Start date: August 01, 2010
• End date: February 29, 2012
• Field of knowledge: Biological Sciences - Pharmacology
• Principal Investigator: Maria Helena Catelli de Carvalho
• Grantee: Tiago Januário da Costa
• Host Institution: Instituto de Ciências Biomédicas (ICB). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

COSTA, TIAGO J.; CERAVOLO, GRAZIELA S.; ECHEM, CINTHYA; HASHIMOTO, CAROLINA M.; COSTA, BEATRIZ P.; SANTOS-EICHLER, ROSANGELA A.; OLIVEIRA, MARIA APARECIDA; JIMENEZ-ALTAYO, FRANCESC; AKAMINE, ELIANA H.; PAULA DANTAS, ANA; et al. Detrimental Effects of Testosterone Addition to Estrogen Therapy Involve Cytochrome P-450-Induced 20-HETE Synthesis in Aorta of Ovariectomized Spontaneously Hypertensive Rat (SHR), a Model of Postmenopausal Hypertension. FRONTIERS IN PHYSIOLOGY, v. 9, MAY 8 2018. (10/03608-1, 14/03758-4)

COSTA, TIAGO J.; CERAVOLO, GRAZIELA S.; DOS SANTOS, ROSANGELA A.; DE OLIVEIRA, MARIA APARECIDA; ARAUJO, PRISCILA X.; GIAQUINTO, LUCIANA R.; TOSTES, RITA C.; AKAMINE, ELIANA H.; FORTES, ZULEICA B.; PAULA DANTAS, ANA; et al. Association of testosterone with estrogen abolishes the beneficial effects of estrogen treatment by increasing ROS generation in aorta endothelial cells. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, v. 308, n. 7, p. H723-H732, APR 1 2015. (10/03608-1)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

COSTA, Tiago Januário da. The vascular protective effects of conjugated equine estrogen (Premarinâ) is blunted by testosterone in ovariectomized spontaneously hypertensive rats (SHR).. 2012. Master's Dissertation - Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB/SDI) São Paulo.