Chromosome evolution on the genus Oligoryzomys (Cricetidae: Sigmodontinae): comparative studies by conventional cytogenetic and chromosome painting

• Grant number: 10/03432-0
• Support Opportunities: Scholarships in Brazil - Master
• Start date until: March 01, 2011
• End date until: September 30, 2012
• Field of knowledge: Biological Sciences - Genetics - Animal Genetics
• Principal Investigator: Maria José de Jesus Silva
• Grantee: Camilla Bruno Di Nizo
• Host Institution: Instituto Butantan. Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil

Abstract

Rodentia is the most numerous order among mammals, comprising about 42% of mammalian species. Rodents are distributed in many types of environments and have specialized habits. The taxonomy of this group has been controversial mainly because of its remarkable diversity and high number of species. Example of this situation occurs in several genera of the tribe Oryzomyini, including Oligoryzomys, in which the number of species and phylogenetic relationships are controversial. Since the 1970's, cytogenetic studies in Neotropical rodents have increased considerably due to the emergence of differential staining techniques and utility of the karyotype as a tool for cytotaxonomy, especially for cryptic species. Several species of Oligoryzomys have been characterized by using such tools. Moreover, the genus presents high chromosomal variability - e.g. centric fusions, pericentric inversions, B chromosomes and polymorphic sex chromosomes - which evinces the importance of cytogenetic studies in this group. The aim of this project is to characterize cytogenetically the species of the genus Oligoryzomys, using conventional cytogenetic methods (CTG, GTG-banding and Ag-NORs staining) and karyotypic evolution through molecular cytogenetics studies with more refined techniques such as FISH with telomeric probes and reciprocal chromosome painting, which are informative for the detection and characterization of syntenic segments that have been maintained during the process of karyotypic differentiation. Furthermore, studies of molecular phylogeny, which have been developed for this group in our laboratory, will provide an important database for the elucidation of phylogenetic relationships of Oligoryzomys.

Scientific publications

(6)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DI-NIZO, CAMILLA BRUNO; VENTURA, KAREN; FERGUSON-SMITH, MALCOLM ANDREW; MARY O'BRIEN, PATRICIA CAROLINE; YONENAGA-YASSUDA, YATIYO; SILVA, MARIA JOSE DE J.. Comparative Chromosome Painting in Six Species of Oligoryzomys (Rodentia, Sigmodontinae) and the Karyotype Evolution of the Genus. PLoS One, v. 10, n. 2, FEB 6 2015. (05/04557-3, 10/03432-0, 11/50146-6)

DI-NIZO, CAMILLA BRUNO; NEVES, CAROLINA LIMA; VILELA, JULIO FERNANDO; SILVA, MARIA JOSE DE J.. New karyologycal data and cytotaxonomic considerations on small mammals from Santa Virginia (Parque Estadual da Serra do Mar, Atlantic Forest, Brazil). COMPARATIVE CYTOGENETICS, v. 8, n. 1, p. 11-30, 2014. (07/03392-6, 05/04557-3, 10/03432-0, 08/00493-9)

MOREIRA, CAMILA NASCIMENTO; DI-NIZO, CAMILLA BRUNO; DE JESUS SILVA, MARIA JOSE; YONENAGA-YASSUDA, YATIYO; VENTURA, KAREN. A remarkable autosomal heteromorphism in Pseudoryzomys simplex 2n=56; FN=54-55 (Rodentia, Sigmodontinae). GENETICS AND MOLECULAR BIOLOGY, v. 36, n. 2, p. 201-206, 2013. (05/04557-3, 10/03432-0)

SUAREZ-VILLOTA, ELKIN Y.; DI-NIZO, CAMILLA B.; NEVES, CAROLINA L.; DE JESUS SILVA, MARIA JOSE. First cytogenetic information for Drymoreomys albimaculatus (Rodentia, Cricetidae), a recently described genus from Brazilian Atlantic Forest. ZOOKEYS, v. N/A, n. 303, p. 12-pg., 2013-01-01. (10/03432-0, 08/00493-9, 05/04557-3)

SUAREZ-VILLOTA, ELKIN Y.; DI-NIZO, CAMILLA B.; NEVES, CAROLINA L.; DE JESUS SILVA, MARIA JOSE. First cytogenetic information for Drymoreomys albimaculatus (Rodentia, Cricetidae), a recently described genus from Brazilian Atlantic Forest. ZOOKEYS, n. 303, p. 65-76, 2013. (05/04557-3, 10/03432-0, 08/00493-9)

CAMILA NASCIMENTO MOREIRA; CAMILLA BRUNO DI-NIZO; MARIA JOSÉ DE JESUS SILVA; YATIYO YONENAGA-YASSUDA; KAREN VENTURA. A remarkable autosomal heteromorphism in Pseudoryzomys simplex 2n = 56; FN = 54-55 (Rodentia, Sigmodontinae). GENETICS AND MOLECULAR BIOLOGY, v. 36, n. 2, p. 201-206, 2013-00-00. (10/03432-0, 05/04557-3)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

NIZO, Camilla Bruno Di. Citotaxonomy and chromosome evolution in Oligoryzomys (Rodentia, Sigmodontinae).. 2013. Master's Dissertation - Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB/SDI) São Paulo.