Evaluation of immunogenic and vaccine potential of Leptospira interrogans sorovar Copenhageni flagellins.

• Grant number: 10/20525-2
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: April 01, 2011
• End date: March 31, 2015
• Field of knowledge: Biological Sciences - Microbiology - Applied Microbiology
• Principal Investigator: Patricia Antonia Estima Abreu de Aniz
• Grantee: Denize Monaris
• Host Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated research grant: 10/51365-0 - Contribution to knowledge of Leptospira interrogans serovar Copenhageni using genomic information, AP.TEM

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ABREU, PATRICIA A. E.; SEGURO, ANTONIO C.; CANALE, DANIELE; DA SILVA, ANA MARIA G.; MATOS, LARISSA DO R. B.; GOTTI, TATIANE B.; MONARIS, DENIZE; DE JESUS, DENISE A.; VASCONCELLOS, SILVIO A.; DE BRITO, THALES; et al. Lp25 membrane protein from pathogenic Leptospira spp. is associated with rhabdomyolysis and oliguric acute kidney injury in a guinea pig model of leptospirosis. PLoS Neglected Tropical Diseases, v. 11, n. 5, MAY 2017. (10/20525-2, 11/17695-6)

MONARIS, D.; SBROGIO-ALMEIDA, M. E.; DIB, C. C.; CANHAMERO, T. A.; SOUZA, G. O.; VASCONCELLOS, S. A.; FERREIRA, L. C. S.; ABREU, P. A. E.. Protective Immunity and Reduced Renal Colonization Induced by Vaccines Containing Recombinant Leptospira interrogans Outer Membrane Proteins and Flagellin Adjuvant. Clinical and Vaccine Immunology, v. 22, n. 8, p. 965-973, AUG 2015. (10/20525-2, 10/51365-0)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

MONARIS, Denize. Evaluation of the immunogenic potential of flagellins Leptospira like adjuvant for development of a subunit vaccine against leptospirosis. 2015. Doctoral Thesis - Universidade de São Paulo (USP). Faculdade de Medicina Veterinária e Zootecnia (FMVZ/SBD) São Paulo.