Production and characterization of chitosan nanofibres reinforced with cellulose nanocrystals for biomedical application

• Grant number: 11/10221-9
• Support type: Scholarships in Brazil - Doctorate
• Effective date (Start): November 01, 2011
• Effective date (End): February 28, 2014
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Physical-Chemistry
• Principal Investigator: Nelson Eduardo Duran Caballero
• Grantee: Daniela Missiani Ridolfi
• Home Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

Nanofibers are a class of polymeric materials that has been highlight at the biomedical area because they exhibit high surface area and high porosity. Chitosan nanofibers have been widely used for biomedical applications due their biocompatibility, biodegradability and non-toxicity. Beyond these properties, chitosan has antimicrobial properties and healing properties that are interesting for use as support to skin repair like, for example, in burns. However, although the great potential of chitosan nanofibers for biomedical applications, they present unsatisfactory mechanical properties and low resistance to water. Then, this project aims at the production and characterization of chitosan nanofibers reinforced with cellulose nanocrystals in order to obtain appropriate biological and mechanical properties for application in tissue engineering.

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

RIDOLFI, Daniela Missiani. Production and characterization of chitosan nanofibers with cellulose nanocrystals for biomedical applications. 2014. Doctoral Thesis - Universidade Estadual de Campinas. Instituto de Química.