This project consists on the preparation and characterization of controlled drug release devices using polyether-siloxane hybrids matrices containing Mn or Co-doped ZnO nanoparticles. Polyether-siloxane hybrids matrices show single properties as high mechanical resistance, transparency and flexibility being a potential material for several scientific and technological areas including the use in drug delivery devices. ZnO semiconductor nanoparticles has strongly attracted attention of the researchers due to their electronic, luminescent, catalytic and optoelectronics varying significantly with particle sized. Other relevant factor is the possibility of the doped ZnO nanoparticles with magnetic elements creating new class of materials known as diluted magnetic semiconductors (DMS), a multifunctional material with magneto-optical properties. The proposal of this work aims prepare a controlled drug release device combining the individual properties of each component in the same material, using the magnetic property of the DMS to drive the delivery device on the sick organ and the luminescent property of the ZnO to monitor the device position inside the human body.
News published in Agência FAPESP Newsletter about the scholarship: