The sunscreens are used to prevent damage caused by UV radiation from the sun, thus protecting the skin from the acute and chronic health effects. To promote a broad spectrum protection, in most sunscreens, at least two organic filters are associated. The avobenzone are chemical absorbers for UVA and octyl methoxycinnamate are chemical absorbers for UVB. Rutin is a flavonoid used traditionally as a potent antioxidant and due to the similarity in the absorption spectrum in the UV rays presents potential for protecting of radiation, and may provide the decrease in concentration of chemical filters in formulations with this objective. The validation method is use quantitative 1H NMR spectroscopy for simultaneous quantification of avobenzone and octyl methoxycinnamate and observation of changes in molecular groups during the study of stability. The 1HNMR spectroscopy offers some advantages, among which we highlight the use of small volumes of solvents and sample preparation is extremely simple.
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