"In vitro" efficacy of sunscreen associated to caffeine

• Grant number: 13/08535-0
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: October 01, 2013
• End date: June 30, 2014
• Field of knowledge: Health Sciences - Pharmacy
• Principal Investigator: André Rolim Baby
• Grantee: Viviane Kaori Tokunaga
• Host Institution: Faculdade de Ciências Farmacêuticas (FCF). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

The primary function of a sunscreen is to protect the skin using active compounds responsible for the absorption, reflection or scattering of solar ultraviolet radiation. Each solar filter is able to absorb only part of the UV radiation, therefore, to provide broad spectrum sunscreen efficacy, with good photostability, a formulation must contain an appropriate combination of two or more solar filters and a photostabilizer compound. The proposed project involves the efficacy and photostability evaluation of broad spectrum sunscreens containing caffeine. Oil-in-water emulsified systems containing three solar filters - octyl p-methoxycinnamate, avobenzone and titanium dioxide - will be prepared, in order to evaluate the photostabilization potential of caffeine on the filters under study.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ROSADO, CATARINA; TOKUNAGA, VIVIANE KAORI; SAUCE, RAFAEL; DE OLIVEIRA, CAMILA AREIAS; SARRUF, FERNANDA DAUD; PARISE-FILHO, ROBERTO; MAURICIO, ELISABETE; DE ALMEIDA, TENIA SANTOS; ROBLES VELASCO, MARIA VALERIA; BABY, ANDRE ROLIM. Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant. FRONTIERS IN PHYSIOLOGY, v. 10, MAY 3 2019. (12/04435-9, 13/08535-0, 13/18689-5)