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Evaluation of autonomic modulation of heart in response to pelvic floor muscle contraction and postural change in women with urinary incontinence.

Grant number: 12/04363-8
Support type:Scholarships in Brazil - Doctorate
Effective date (Start): August 01, 2012
Effective date (End): September 07, 2015
Field of knowledge:Health Sciences - Physiotherapy and Occupational Therapy
Principal researcher:Patricia Driusso
Grantee:Soraia Pilon Jürgensen
Home Institution: Centro de Ciências Biológicas e da Saúde (CCBS). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil


Introduction: Urgency urinary incontinence (UUI) is involuntary loss of urine associated with miccional urgency and is associated with increase of urinary frequency and nocturia. The hypothesis of this study is that dysfunction of autonomic system responsible by control of voiding will compromise the vesical and Sphincteric activity, causing the UUI. Objetive: compare the cardiac autonomic modulation in women with and without urinary incontinence (UI), using the heart rate variability during the pelvic floor muscles contraction and postural change Method: transversal study with 72 women that divided in three groups: Stress Urinary Incontinence Group (SUIG); Urgency Urinary Incontinence Group (UUIG); Control Group (CG). The inclusion criteria: women with more 40 years old, body mass index equal or < 30kg/m2, women without cardiovascular disease, osteo-myo-articular, respiratory, neurological, vascular, urinary or vaginal infection; not be alcoholic or drug user, and not having undergone any treatment for UI or hormone replacement. The volunteers will be submitted four days of evaluation: First day: anamnesis, the King's Health Questionnaire (KHQ), the questionnaire Incontinence Severity Index (ISI) and will receive guidance on the test absorber 24 hours; Second day: devolution of absorbers and performance of the clinical exercise test; Third day: assessment of HRV in postural change, functional evaluation of pelvic floor muscle and surface electromyography; Fourth day: evaluation of HRV during the contraction of MAP. For statistical analysis we will use the Shapiro-Wilk test to assess the normality of the data. The correlation will be evaluated with Spearman correlation test. The level of significance will be of 5% (p d 0.05).

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
S.P. JÜRGENSEN; A. BORGHI-SILVA; A.M.F.G. BASTOS; G.N. CORREIA; V.S. PEREIRA-BALDON; R. CABIDDU; A.M. CATAI; P. DRIUSSO. Relationship between aerobic capacity and pelvic floor muscles function: a cross-sectional study. Brazilian Journal of Medical and Biological Research, v. 50, n. 11, . (12/04363-8)

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