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Genomic study for intake and feed efficiency in Nellore cattle

Grant number: 12/03551-5
Support Opportunities:Scholarships in Brazil - Doctorate
Effective date (Start): August 01, 2012
Effective date (End): October 31, 2013
Field of knowledge:Agronomical Sciences - Animal Husbandry - Genetics and Improvement of Domestic Animals
Principal Investigator:José Bento Sterman Ferraz
Grantee:Miguel Henrique de Almeida Santana
Host Institution: Faculdade de Zootecnia e Engenharia de Alimentos (FZEA). Universidade de São Paulo (USP). Pirassununga , SP, Brazil


Last advances in genetics and molecular biology have made possible the complete sequencing of bovine genome, as well as open wide a new range on this research area. However, studies involving cattle's genomic data with feed intake and feed efficiency are still rare. Several single nucleotide polymorphisms (SNP) have been identified in taurus beef cattle's genes related to weight gain, carcass quality and other production traits. This project aimed to verify SNP in cattle's genome and to associate these with feed intake and feed efficiency of Nellore cattle, the most expressive and important breed under Brazilian cattle. Data will be used for dry matter intake, feed conversion ratio, partial efficiency of growth and residual feed intake of 400 of this breed. These animals will have their genomic DNA extracted and then individually genotyped by commercial chips (BovineSNP50 Beadchip®, Illumina Inc). These genomic data will be used in conjunction with the phenotypic data for the characterization of SNP to calculate gene and genotypic frequencies, additive, allele substitution and dominance effects. In addition, pedigree data will be included to estimate the molecular breeding value of each animal using GBLUP and Bayesian (Bayes A, B, C, CÀ and DÀ) methods.

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Scientific publications (4)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
SANTANA, M. H. A.; UTSUNOMIYA, Y. T.; NEVES, H. H. R.; GOMES, R. C.; GARCIA, J. F.; FUKUMASU, H.; SILVA, S. L.; LEME, P. R.; COUTINHO, L. L.; ELER, J. P.; et al. Genome-wide association study for feedlot average daily gain in Nellore cattle (Bos indicus). JOURNAL OF ANIMAL BREEDING AND GENETICS, v. 131, n. 3, p. 210-216, . (12/03551-5, 11/16643-2, 12/02039-9)
SANTANA, M. H. A.; GOMES, R. C.; OZAWA, G. M.; FUKUMASU, H.; SILVA, S. L.; LEME, P. R.; ROSSI JUNIOR, P.; PIRES, P. R. L.; ALEXANDRE, P. A.; OLIVEIRA, P. S.; et al. Single nucleotide polymorphisms in genes linked to ion transport and regulation of appetite and their associations with weight gain, feed efficiency and intake of Nellore cattle. LIVESTOCK SCIENCE, v. 165, p. 33-36, . (12/03551-5, 12/02039-9)
SANTANA, M. H. A.; OLIVEIRA JUNIOR, G. A.; GOMES, R. C.; SILVA, S. L.; LEME, P. R.; STELLA, T. R.; MATTOS, E. C.; ROSSI JUNIOR, P.; BALDI, F. S.; ELER, J. P.; et al. Genetic parameter estimates for feed efficiency and dry matter intake and their association with growth and carcass traits in Nellore cattle. LIVESTOCK SCIENCE, v. 167, p. 80-85, . (12/03551-5, 12/02039-9)
SANTANA, MIGUEL H. A.; UTSUNOMIYA, YURI T.; NEVES, HAROLDO H. R.; GOMES, RODRIGO C.; GARCIA, JOSE F.; FUKUMASU, HEIDGE; SILVA, SAULO L.; OLIVEIRA JUNIOR, GERSON A.; ALEXANDRE, PAMELA A.; LEME, PAULO R.; et al. Genome-wide association analysis of feed intake and residual feed intake in Nellore cattle. BMC GENETICS, v. 15, . (12/03551-5, 11/16643-2, 12/02039-9)
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
SANTANA, Miguel Henrique de Almeida. Genetic and genomic study of intake and feed efficiency in Nellore (Bos indicus) cattle. 2013. Doctoral Thesis - Universidade de São Paulo (USP). Faculdade de Zootecnica e Engenharia de Alimentos (FZE/BT) Pirassununga.

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