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Prognosis of the Correlation between the Epicardial Fat Thickness and Events of Coronary Atherosclerosis

Grant number: 12/00348-4
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): September 01, 2012
Effective date (End): August 31, 2013
Field of knowledge:Health Sciences - Medicine - Medical Clinics
Principal Investigator:João Cesar Nunes Sbano
Grantee:Bianca Brunelli Eduardo
Home Institution: Instituto do Coração Professor Euryclides de Jesus Zerbini (INCOR). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil

Abstract

This research project intends to evaluate the capacity to predict events related to atherosclerosis in coronary arteries starting from the measurement of the epicardial fat thickness.The coronary arterial disease presents a huge medical and social relevance. It is one of the main causes of death in the current days, being directly related to atherosclerotic process, visceral adiposity and the severity of coronary arterial disease.The measurement of the epicardial fat thickness can be realized by bidimensional echocardiography exam that has showed up more advantages than other techniques as Computed Tomography and Magnetic Resonance. Will be measured other parameters that allow to analyze diastolic and systolic function of the left ventricle. These parameters can have implications with what will be studied.In this study, will be evaluated 100 pacients from a stress echocardiography study performed at InCor - HCFMUSP. Will be obtained the thickness of the epicardial fat by the analysis of the echocardiography exam and, subsequently, will be examined the clinical evolution of the pacient by a review of medical records. Therefore, it is intended to establish relations between the epicardial fat thickness and coronary atherosclerosis events aiming to predict events and prognosis.