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Dose-volume relationship in planning systems for 3D brachytherapy using mcnp5 code, brachyvision and oncentra

Grant number: 11/23765-7
Support Opportunities:Scholarships abroad - Research Internship - Doctorate
Start date: July 01, 2012
End date: June 30, 2013
Field of knowledge:Engineering - Nuclear Engineering - Applications of Radioisotopes
Principal Investigator:Hélio Yoriyaz
Grantee:Gabriel Paiva Fonseca
Supervisor: Verhaegen Frans
Host Institution: Instituto de Pesquisas Energéticas e Nucleares (IPEN). Secretaria de Desenvolvimento Econômico (São Paulo - Estado). São Paulo , SP, Brazil
Institution abroad: MAASTRO Clinic, Netherlands  
Associated to the scholarship:11/01913-4 - Monte Carlo modelling of the patient and treatment delivery complexities for high dose rate brachytherapy, BP.DR

Abstract

In view the good clinical results obtained and the technological advancement, several innovations have been incorporated to brachytherapy treatment technique, for example, 3D planning systems and computer-guided sources. In detriment to scientific advances there are no protocols that relate dose with tumor volume, organs or the A point, established by ICRU38 and used to prescribe dose in treatment planning system. Several international studies have been trying to correlate the dose volume using 3D planning systems and medical images, as those obtained by CT or MRI. In order to establish an international cooperation between two research centers this project involves a one year stage at Maastro Clinic in the Netherlands, an active research center, which have been publishing several studies related to brachytherapy of which the student intends to participate actively, as well as developing a large part of his doctoral plan, enjoying the researchers experience and the structure available in the institution. (AU)

News published in Agência FAPESP Newsletter about the scholarship:
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VEICULO: TITULO (DATA)
VEICULO: TITULO (DATA)

Scientific publications (5)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
FONSECA, GABRIEL P.; RENIERS, BRIGITTE; LANDRY, GUILLAUME; WHITE, SHANE; BELLEZZO, MURILLO; ANTUNES, PAULA C. G.; DE SALES, CAMILA P.; WELTEMAN, EDUARDO; YORIYAZ, HELIO; VERHAEGEN, FRANK. A medical image-based graphical platform-Features, applications and relevance for brachytherapy. BRACHYTHERAPY, v. 13, n. 6, p. 632-639, . (11/22778-8, 11/23765-7, 11/01913-4)
FONSECA, G. P.; RUBO, R. A.; MINAMISAWA, R. A.; DOS SANTOS, G. R.; ANTUNES, P. C. G.; YORIYAZ, H.. Determination of transit dose profile for a Ir-192 HDR source. Medical Physics, v. 40, n. 5, . (11/22778-8, 11/23765-7, 11/01913-4)
FONSECA, GABRIEL PAIVA; LANDRY, GUILLAUME; WHITE, SHANE; D'AMOURS, MICHEL; YORIYAZ, HELIO; BEAULIEU, LUC; RENIERS, BRIGITTE; VERHAEGEN, FRANK. The use of tetrahedral mesh geometries in Monte Carlo simulation of applicator based brachytherapy dose distributions. Physics in Medicine and Biology, v. 59, n. 19, p. 5921-5935, . (11/22778-8, 11/23765-7, 11/01913-4)
FONSECA, GABRIEL PAIVA; TEDGREN, ASA CARLSSON; RENIERS, BRIGITTE; NILSSON, JOSEF; PERSSON, MARIA; YORIYAZ, HELIO; VERHAEGEN, FRANK. Dose specification for Ir-192 high dose rate brachytherapy in terms of dose-to-water-in-medium and dose-to-medium-in-medium. Physics in Medicine and Biology, v. 60, n. 11, p. 4565-4579, . (11/22778-8, 11/23765-7, 11/01913-4)
FONSECA, G. P.; LANDRY, G.; RENIERS, B.; HOFFMANN, A.; RUBO, R. A.; ANTUNES, P. C. G.; YORIYAZ, H.; VERHAEGEN, F.. The contribution from transit dose for Ir-192 HDR brachytherapy treatments. Physics in Medicine and Biology, v. 59, n. 7, p. 1831-1844, . (11/22778-8, 11/23765-7, 11/01913-4)