Clinical evaluation of the effect of a 38% hydrogen peroxide with 10% carbamide peroxide on enamel surface

• Grant number: 12/08191-7
• Support Opportunities: Scholarships abroad - Research Internship - Doctorate
• Start date: May 05, 2012
• End date: November 04, 2012
• Field of knowledge: Health Sciences - Dentistry - Dental Clinics
• Principal Investigator: Renato Herman Sundfeld
• Grantee: Lucas Silveira Machado
• Supervisor: Paulo G. Coelho
• Host Institution: Faculdade de Odontologia (FOA). Universidade Estadual Paulista (UNESP). Campus de Araçatuba. Araçatuba , SP, Brazil
• Institution abroad: New York University, United States
• Associated to the scholarship: 10/07112-0 - Clinical comparison of at-home and in-office dental bleaching procedures: a randomized trial of a split-mouth design, BP.DR

Abstract

The aim of this clinical and microscopic study is to assess the possible effects due to the association of different bleaching techniques with carbamide and hydrogen peroxide through evaluation of the following response variables: enamel surface alterations and roughness. Twenty volunteers take part in this research. The highlighted factors are bleaching treatment using a 38% hydrogen peroxide non photocatalysed bleaching gel (Opalescence Boost PF - Bleaching Gel A), a 10% carbamide peroxide bleaching gel (Opalescence - Bleaching Gel B) and a placebo. The variables will be analyzed on incisors. Initially, the volunteers had their maxillary left and right hemi-arches submitted to three sessions of 15 minutes each with bleaching gel A and placebo gel (Phase 1), characterizing a split-mouth design. During the 7 days following Phase 1, the volunteers used the bleaching gel B, at home, for 4 hours a day (Phase 2); these clinical steps will be repeated once again in the next week. Alterations of enamel surface will be analyzed with scanning electron microscopy (SEM) through clinically obtained replicas, obtained before and after all the bleaching procedures are done. , the surface roughness of the replicas will be measured by an interferometer (M1m Axio Imager, Carl Zeiss, Germany) and calculated by a software in three dimensions (3D Axio software, CarlZeiss, Germany), with data expressed as Sa (arithmetic average surface roughnessprofile 3D). Appropriate static test will be applied to interpret the results. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MACHADO, LUCAS SILVEIRA; ANCHIETA, RODOLFO BRUNIERA; DOS SANTOS, PAULO HENRIQUE; BRISO, ANDRE LUIZ FRAGA; TOVAR, NICK; JANAL, MALVIN N.; COELHO, PAULO GUILHERME; SUNDFELD, RENATO HERMAN. Clinical Comparison of At-Home and In-Office Dental Bleaching Procedures: A Randomized Trial of a Split-Mouth Design. INTERNATIONAL JOURNAL OF PERIODONTICS & RESTORATIVE DENTISTRY, v. 36, n. 2, p. 251-260, MAR-APR 2016. (12/08191-7, 10/07112-0)