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Clinical comparison of at-home and in-office dental bleaching procedures: a randomized trial of a split-mouth design

Grant number: 10/07112-0
Support Opportunities:Scholarships in Brazil - Doctorate
Effective date (Start): October 01, 2010
Effective date (End): April 30, 2013
Field of knowledge:Health Sciences - Dentistry - Dental Clinics
Principal Investigator:Renato Herman Sundfeld
Grantee:Lucas Silveira Machado
Host Institution: Faculdade de Odontologia (FOA). Universidade Estadual Paulista (UNESP). Campus de Araçatuba. Araçatuba , SP, Brazil
Associated scholarship(s):12/08191-7 - Clinical evaluation of the effect of a 38% hydrogen peroxide with 10% carbamide peroxide on enamel surface, BE.EP.DR

Abstract

The objective of this clinical, microscopic and digital/computational study is to evaluate the possible effects of the combination of whitening techniques with carbamide and hydrogen peroxide, through these reply variables: color changing, dentinal sensitivity and alterations in the surface of the enamel structure. Tweenty volunteers will participate of this clinical research; where we will evaluate the whitening treatment based on a bleachening gel non photo-catalyzed based on hydrogen peroxide at 38% (Opalescence Boost PF - bleachening gel A), a bleaching gel based on carbamide peroxide at 10% (Opalescence - bleachening gel B) and a placebo gel. The variables will be evaluated at incisives and canines teeth. Inicially, volunteers will have their left and right superior hemi arcades submitted to 3 applications (15 minutes each) of bleachening with gels A and placebo (Phase 1), in a split- mouth study design. During the seven days following the Phase 1, volunteers will use the whitening gel B at home by four hours daily (Phase 2); these clinical steps will be repeated once again in the week following phase 2. The measurement of color changing will take place at visual and digital/computational method, before to the start of the experiment and after the application of materials; dentinal sensitivity will be analyzed during and after the application of whitening techniques, whereas the changes in the enamel surface will be analyzed in electrons microscopes (SEM), using replicas obtained before and after the application of bleaching techniques. Considering the possible qualitative ordinal variables of responses, Mann- Whitney and Kruskal-Wallis tests of significance at 5% will be used for analysis results.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MACHADO, LUCAS SILVEIRA; ANCHIETA, RODOLFO BRUNIERA; DOS SANTOS, PAULO HENRIQUE; BRISO, ANDRE LUIZ FRAGA; TOVAR, NICK; JANAL, MALVIN N.; COELHO, PAULO GUILHERME; SUNDFELD, RENATO HERMAN. Clinical Comparison of At-Home and In-Office Dental Bleaching Procedures: A Randomized Trial of a Split-Mouth Design. INTERNATIONAL JOURNAL OF PERIODONTICS & RESTORATIVE DENTISTRY, v. 36, n. 2, p. 251-260, . (12/08191-7, 10/07112-0)
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
MACHADO, Lucas Silveira. Avaliação clínica dos efeitos da associação do peróxido de hidrogênio a 38% com o peróxido de carbamida a 10%. 2013. Doctoral Thesis - Universidade Estadual Paulista (Unesp). Faculdade de Odontologia. Araçatuba Araçatuba.

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