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Corpus callosum characterization from magnetic ressonance images

Grant number: 12/23059-8
Support type:Scholarships in Brazil - Doctorate
Effective date (Start): March 01, 2013
Effective date (End): February 29, 2016
Field of knowledge:Engineering - Electrical Engineering
Principal researcher:Roberto de Alencar Lotufo
Grantee:André Luis da Costa
Home Institution: Faculdade de Engenharia Elétrica e de Computação (FEEC). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil


The corpus callosum is the largest white matter structure in the human brain, responsible for facilitating inter-hemispheric communication. Many studies associated corpus callosum anomalies with various diseases and disorders. In general, anomalies are observed in magnetic resonance imaging, by observing micro-structure measures and some macro-structure measures, the most common area or volume. Just recently there has been studies that relate the corpus callosum micro-structure measurements with its extension. In this project we are proposing the development of specific forms of characterization to the corpus callosum, based on the combination of micro-structure measurements with the macro-structure of the corpus callosum. We intend to find a signature of the corpus callosum that has high correlation intra-individual and higher correlation inter-individual to individuals belonging to the same group. That signature should be based on attributes of the extracted resonance images, especially images of diffusion. As a secondary objective, we will search for visual representations of the signatures, so that specialists can quickly identify anomalies by visual inspection.

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Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
COSTA, André Luis da. Framework para a análise da microestrutura do corpo caloso ao longo de sua extensão. 2018. Doctoral Thesis - Universidade Estadual de Campinas (UNICAMP). Faculdade de Engenharia Elétrica e de Computação Campinas, SP.

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