The corpus callosum is the largest white matter structure in the human brain, responsible for facilitating inter-hemispheric communication. Many studies associated corpus callosum anomalies with various diseases and disorders. In general, anomalies are observed in magnetic resonance imaging, by observing micro-structure measures and some macro-structure measures, the most common area or volume. Just recently there has been studies that relate the corpus callosum micro-structure measurements with its extension. In this project we are proposing the development of specific forms of characterization to the corpus callosum, based on the combination of micro-structure measurements with the macro-structure of the corpus callosum. We intend to find a signature of the corpus callosum that has high correlation intra-individual and higher correlation inter-individual to individuals belonging to the same group. That signature should be based on attributes of the extracted resonance images, especially images of diffusion. As a secondary objective, we will search for visual representations of the signatures, so that specialists can quickly identify anomalies by visual inspection.
News published in Agência FAPESP Newsletter about the scholarship: