Corpus callosum characterization from magnetic ressonance images

• Grant number: 12/23059-8
• Support type: Scholarships in Brazil - Doctorate
• Effective date (Start): March 01, 2013
• Effective date (End): February 29, 2016
• Field of knowledge: Engineering - Electrical Engineering
• Principal researcher: Roberto de Alencar Lotufo
• Grantee: André Luis da Costa
• Home Institution: Faculdade de Engenharia Elétrica e de Computação (FEEC). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

The corpus callosum is the largest white matter structure in the human brain, responsible for facilitating inter-hemispheric communication. Many studies associated corpus callosum anomalies with various diseases and disorders. In general, anomalies are observed in magnetic resonance imaging, by observing micro-structure measures and some macro-structure measures, the most common area or volume. Just recently there has been studies that relate the corpus callosum micro-structure measurements with its extension. In this project we are proposing the development of specific forms of characterization to the corpus callosum, based on the combination of micro-structure measurements with the macro-structure of the corpus callosum. We intend to find a signature of the corpus callosum that has high correlation intra-individual and higher correlation inter-individual to individuals belonging to the same group. That signature should be based on attributes of the extracted resonance images, especially images of diffusion. As a secondary objective, we will search for visual representations of the signatures, so that specialists can quickly identify anomalies by visual inspection.

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

COSTA, André Luis da. Framework para a análise da microestrutura do corpo caloso ao longo de sua extensão. 2018. Doctoral Thesis - Universidade Estadual de Campinas (UNICAMP). Faculdade de Engenharia Elétrica e de Computação Campinas, SP.