Microspheres of calcium phosphate obtained by spray drying

• Grant number: 13/03208-1
• Support type: Scholarships abroad - Research Internship - Master's degree
• Effective date (Start): June 09, 2013
• Effective date (End): August 08, 2013
• Field of knowledge: Engineering - Materials and Metallurgical Engineering - Nonmetallic Materials
• Principal researcher: Mariana Motisuke
• Grantee: Caroline de Oliveira Renó
• Supervisor abroad: Miguel A. Rodríguez Barbero
• Home Institution: Instituto de Ciência e Tecnologia (ICT). Universidade Federal de São Paulo (UNIFESP). Campus São José dos Campos. São José dos Campos , SP, Brazil
• Research place: Instituto de Cerámica y Vidrio (ICV), Spain
• Associated to the scholarship: 12/21198-0 - Bioactive and reabsorbable calcium phosphate microspheres for drug delivery, BP.MS

Abstract

Calcium phosphates (CaP) are potential candidates for bone treatments once they are biocompatible, bioactive and resorbable. Granules of CaP, which presents irregular forms, have shown an increase in their clinical application due to their higher rate of "in vivo" resorption. However, when this materials are associated with bioactive molecules, such as drugs, the control of their forms essential. Therefore, it becomes logical to develop CaP microspheres capable of treating diseases or induce new bone tissue growth. The aim of this project is to obtain microspheres of calcium phosphate cement (CPC) using the process of spray drying. This technique has high efficiency and permits the formation of granules nearly spherical. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

C. O. RENÓ; R. G. CARRODEGUAS; M. MOTISUKE; M. A. RODRÍGUEZ. Preparation and properties of α-tricalcium phosphate microspheres by spray drying. Cerâmica, v. 65, n. 376, p. 599-604, Dez. 2019.