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Mercury metalloproteomics studies in hepatic tissue samples of fish collected in the the AHE JIRAU - Madeira River Basin area of influence

Grant number: 12/24035-5
Support type:Scholarships in Brazil - Master
Effective date (Start): June 01, 2013
Effective date (End): February 28, 2014
Field of knowledge:Agronomical Sciences - Fishery Resources and Fishery Engineering - Aquaculture
Principal Investigator:Pedro de Magalhães Padilha
Grantee:José Cavalcante Souza Vieira
Home Institution: Instituto de Biociências (IBB). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil

Abstract

The work searching to optimize of analytical methods for application of metallomics in thedevelopment of potential biomarkers of mercury toxicity in liver tissue samples of fish collected in the influence area of Hydroelectric JIRAU - Madeira River basin, Rondônia/Brasil. To achieve this primary objective, the project brings together a multi-institutional team engaged in optimizing of: electrophoretic procedures in 2D-PAGE for fractionation and identification of proteins responsible for the mercury transport in fish samples collected in the reservoir AHE JIRAU - Madeira River Basin; methods for mercury quantitative evaluation in protein spots obtained in the proteins fractionation by 2D-PAGE and proteins characterization carriers mercury by MALDI-TOF MS. The proposed work will provide technical and scientific grants in the health and environment areas of extreme importance, enabling the development of monitoring protocols applicable to hydropower plants in the Amazon region. (AU)

News published in Agência FAPESP Newsletter about the scholarship:
Study improves method for detecting mercury in fish  

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
SOUZA VIEIRA, JOSE CAVALCANTE; BRAGA, CAMILA PEREIRA; DE OLIVEIRA, GRASIELI; FEDERICI PADILHA, CILENE DO CARMO; DE MORAES, PAULA MARTIN; ZARA, LUIZ FABRICIO; LEITE, ALINE DE LIMA; RABELO BUZALAF, MARILIA AFONSO; PADILHA, PEDRO DE MAGALHAES. Mercury Exposure: Protein Biomarkers of Mercury Exposure in Jaraqui Fish from the Amazon Region. BIOLOGICAL TRACE ELEMENT RESEARCH, v. 183, n. 1, p. 164-171, MAY 2018. Web of Science Citations: 6.
VIEIRA, JOSE C. S.; CAVECCI, BRUNA; QUEIROZ, JOAO V.; BRAGA, CAMILA P.; PADILHA, CILENE C. F.; LEITE, ALINE L.; FIGUEIREDO, WLLYANE S.; BUZALAF, MARILIA A. R.; ZARA, LUIZ F.; PADILHA, PEDRO M. Determination of the Mercury Fraction Linked to Protein of Muscle and Liver Tissue of Tucunar, (Cichla spp.) from the Amazon Region of Brazil. Archives of Environmental Contamination and Toxicology, v. 69, n. 4, p. 422-430, NOV 2015. Web of Science Citations: 8.
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
VIEIRA, José Cavalcante Souza. Estudo metaloproteômico do mércurio em amostras de tecido hepático de peixes coletados na área de influência do AHE JIRAU - Bacia do rio Madeira. 2014. 92 f. Master's Dissertation - Universidade Estadual Paulista "Júlio de Mesquita Filho" Instituto de Biociências (Campus de Botucatu). Botucatu.

Please report errors in scientific publications list by writing to: cdi@fapesp.br.