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Selection signatures in Canchim beef cattle

Grant number: 13/09050-0
Support type:Scholarships in Brazil - Master
Effective date (Start): July 01, 2013
Effective date (End): July 31, 2014
Field of knowledge:Agronomical Sciences - Animal Husbandry
Principal Investigator:Danísio Prado Munari
Grantee:Ismael Urbinati
Home Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil

Abstract

Considering the advent of genomics in animal breeding and the recent technology of high density genotyping panels, genome wide association studies between single nucleotide polymorphism (SNP) and phenotypes could bring benefits in animal production. The artificial selection aims to obtain individuals bearing genes of interest, consequently, the population allele frequencies changes over the years. However, some genomic regions are in linkage disequilibrium, meaning that some SNP do not segregate at random and loci are maintained through generation. This phenomenon is also known as haplotype. When haplotypes are transmitted together with genes they are called selection signatures. Selection signatures can be estimated by using high density SNP panels through genotype scans and helps to indentify genes that are responsible, directly or indirectly, to the phenotypic variations of traits of economic interest under selection. Furthermore, it enables greater understanding of evolution and biology involved in the manifestations of phenotype and provide tools to increase efficiency of selection. Thus, the aim of this study is to identify selection signatures in Canchim cattle under selection. Data of 400 Canchim animals genotyped with high density panels will be analyzed. Selection signatures will be detected by determining the Extended Haplotype Homozygosity Statistic, through the R statistical software package "rehh".

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
URBINATI, ISMAEL; STAFUZZA, NEDENIA BONVINO; OLIVEIRA, MARCOS TULIO; SELEGUIM CHUD, TATIANE CRISTINA; HIGA, ROBERTO HIROSHI; DE ALMEIDA REGITANO, LUCIANA CORREIA; DE ALENCAR, MAURICIO MELLO; BUZANSKAS, MARCOS ELI; MUNARI, DANISIO PRADO. Selection signatures in Canchim beef cattle. JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY, v. 7, MAY 5 2016. Web of Science Citations: 9.
BERNARDES, P. A.; GROSSI, D. A.; SAVEGNAGO, R. P.; BUZANSKAS, M. E.; URBINATI, I.; BEZERRA, L. A. F.; LOBO, R. B.; MUNARI, D. P. Estimates of genetic parameters and genetic trends for reproductive traits and weaning weight in Tabapua cattle. JOURNAL OF ANIMAL SCIENCE, v. 93, n. 11, p. 5175-5185, NOV 2015. Web of Science Citations: 7.
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
URBINATI, Ismael. Assinaturas de seleção em bovinos da raça Canchim. 2014. Master's Dissertation - Universidade Estadual Paulista "Júlio de Mesquita Filho" Faculdade de Ciências Agrárias e Veterinárias..

Please report errors in scientific publications list by writing to: cdi@fapesp.br.