Effect of the association between the professional application of TiF4 varnish and the daily rinse with TiF4/ NaF solution on enamel erosion in vitro

• Grant number: 12/22642-1
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: July 01, 2013
• End date: July 31, 2015
• Field of knowledge: Health Sciences - Dentistry - Pediatric Dentistry
• Principal Investigator: Ana Carolina Magalhães
• Grantee: Milena Gargaro dos Santos
• Host Institution: Faculdade de Odontologia de Bauru (FOB). Universidade de São Paulo (USP). Bauru , SP, Brazil
• Associated scholarship(s): 14/23472-8 - Effect of the association between the professional application of TiF4 varnish and daily rinse with a solution containing TiF4 /NaF on dentin erosion in vitro, BE.EP.IC

Abstract

The aim of this study is to investigate the effect of the association between the professional application of TiF4 varnish (one application) and the at-home application of a solution containing TiF4/NaF (daily application) against enamel erosion in vitro. For that, 90 polished bovine enamel samples will be protected in 2/3 of the surface using nail varnish and distribute into 6 experimental groups (n=15/group): Group 1 - control (no treatment); Group 2 - rinse solution containing TiF4/NaF (500 ppm F-, pH to be measured); Group 3 - NaF varnish (24500 ppm F-, pH 5.0) + group 2; Group 4 - TiF4 varnish (24500 ppm F-, pH 1.2) + group 2; Group 5 - NaF varnish; Group 6 - TiF4 varnish. The samples belong to the varnishes` groups will be treated once for 6h, before the pH-cycling. After 6h, the varnishes will be removed. The samples belong to the fluoride solution will be treated daily for 7 days (2x1min/day), after the first and the last erosive challenges. The erosive challenges will be done 4x90s/day, using 0.1% citric acid solution (pH 2.5). Between the erosive challenges, the samples will be immersed in artificial saliva (remineralization). After 5 days, the enamel wear will be measured using contact profilometer (µm). The data will be statistically analyzed (p<0.05). (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MAGALHAES, ANA CAROLINA; DOS SANTOS, MILENA GARGARO; COMAR, LIVIA PICCHI; RABELO BUZALAF, MARILIA AFONSO; GANSS, CAROLINA; SCHLUETER, NADINE. Effect of a Single Application of TiF4 Varnish versus Daily Use of a Low-Concentrated TiF4/NaF Solution on Tooth Erosion Prevention in vitro. Caries Research, v. 50, n. 5, p. 462-470, 2016. (12/22642-1, 12/20698-0, 14/23472-8)